| Description : |
Binds to the promoters of target genes and functions as repressor. Promotes cell proliferation and antagonizes cell death. Promotes phosphorylation of AKT1 at 'Ser-473'. |
| Source : |
HEK293 |
| Species : |
Human |
| Tag : |
Myc/DDK |
| Molecular Mass : |
115.3 kDa |
| AA Sequence : |
MQSKVTGNMPTQSLLMYMDGPEVIG SSLGSPMEMEDALSMKGTAVVPFRA TQEKNVIQIEGYMPLDCMFCSQTFT HSEDLNKHVLMQHRPTLCEPAVLRV EAEYLSPLDKSQVRTEPPKEKNCKE NEFSCEVCGQTFRVAFDVEIHMRTH KDSFTYGCNMCGRRFKEPWFLKNHM RTHNGKSGARSKLQQGLESSPATIN EVVQVHAAESISSPYKICMVCGFLF PNKESLIEHRKVHTKKTAFGTSSAQ TDSPQGGMPSSREDFLQLFNLRPKS HPETGKKPVRCIPQLDPFTTFQAWQ LATKGKVAICQEVKESGQEGSTDND DSSSEKELGETNKGSCAGLSQEKEK CKHSHGEAPSVDADPKLPSSKEKPT HCSECGKAFRTYHQLVLHSRVHKKD RRAGAESPTMSVDGRQPGTCSPDLA APLDENGAVDRGEGGSEDGSEDGLP EGIHLDKNDDGGKIKHLTSSRECSY CGKFFRSNYYLNIHLRTHTGEKPYK CEFCEYAAAQKTSLRYHLERHHKEK QTDVAAEVKNDGKNQDTEDALLTAD SAQTKNLKRFFDGAKDVTGSPPAKQ LKEMPSVFQNVLGSAVLSPAHKDTQ DFHKNAADDSADKVNKNPTPAYLDL LKKRSAVETQANNLICRTKADVTPP PDGSTTHNLEVSPKEKQTETAADCR YRPSVDCHEKPLNLSVGALHNCPAI SLSKSLIPSITCPFCTFKTFYPEVL MMHQRLEHKYNPDVHKNCRNKSLLR SRRTGCPPALLGKDVPPLSSFCKPK PKSAFPAQSKSLPSAKGKQSPPGPG KAPLTSGIDSSTLAPSNLKSHRPQQ NVGVQGAATRQQQSEMFPKTSVSPA PDKTKRPETKLKPLPVAPSQPTLGS SNINGSIDYPAKNDSPWAPPGRDYF CNRSASNTAAEFGEPLPKRLKSSVV ALDVDQPGANYRRGYDLPKYHMVRG ITSLLPQDCVYPSQALPPKPRFLSS SEVDSPNVLTVQKPYGGSGPLYTCV PAGSPASSSTLEGKRPVSYQHLSNS MAQKRNYENFIGNAHYRPNDKKTTR TRPLEQKLISEEDLAANDILDYKDD DDKV |
| Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining |
| Stability : |
Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Storage : |
Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
| Concentration : |
50 μg/mL as determined by BCA |
| Storage Buffer : |
100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
