Recombinant Human ZNRF3 Protein (56-219 aa), His-SUMO-tagged
Cat.No. : | ZNRF3-1910H |
Product Overview : | Recombinant Human ZNRF3 Protein (56-219 aa) is produced by E. coli expression system. This protein is fused with a 6xHis-SUMO tag at the N-terminal. Research Area: Epigenetics and Nuclear Signaling. Protein Description: Partial. |
- Specification
- Gene Information
- Related Products
Description : | E3 ubiquitin-protein ligase that acts as a negative regulator of the Wnt signaling pathway by mediating the ubiquitination and subsequent degradation of Wnt receptor complex components Frizzled and LRP6. Acts on both canonical and non-canonical Wnt signaling pathway. Acts as a tumor suppressor in the intestinal stem cell zone by inhibiting the Wnt signaling pathway, thereby resticting the size of the intestinal stem cell zone. |
Source : | E. coli |
Species : | Human |
Tag : | His-SUMO |
Form : | Tris-based buffer,50% glycerol |
Molecular Mass : | 34.2 kDa |
Protein length : | 56-219 aa |
AA Sequence : | KETAFVEVVLFESSPSGDYTTYTTG LTGRFSRAGATLSAEGEIVQMHPLG LCNNNDEEDLYEYGWVGVVKLEQPE LDPKPCLTVLGKAKRAVQRGATAVI FDVSENPEAIDQLNQGSEDPLKRPV VYVKGADAIKLMNIVNKQKVARARI QHRPPRQPTEYFDM |
Purity : | > 90% as determined by SDS-PAGE. |
Notes : | Repeated freezing and thawing is not recommended. Store working aliquots at 4 centigrade for up to one week. |
Storage : | The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20 centigrade/-80 centigrade. The shelf life of lyophilized form is 12 months at -20 centigrade/-80 centigrade. |
Concentration : | A hardcopy of COA with reconstitution instruction is sent along with the products. |
Gene Name : | ZNRF3 zinc and ring finger 3 [ Homo sapiens ] |
Official Symbol : | ZNRF3 |
Synonyms : | RNF203; BK747E2.3; |
Gene ID : | 84133 |
mRNA Refseq : | NM_032173.3 |
Protein Refseq : | NP_115549.2 |
MIM : | 612062 |
UniProt ID : | Q9ULT6 |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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