Recombinant Human ZW10 Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: ZW10-762H
• Product Overview: ZW10 MS Standard C13 and N15-labeled recombinant protein (NP_004715) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: This gene encodes a protein that is one of many involved in mechanisms to ensure proper chromosome segregation during cell division. This protein is an essential component of the mitotic checkpoint, which prevents cells from prematurely exiting mitosis.
• Source: HEK293
• Species: Human
• Tag: Myc/DDK
• Molecular Mass: 88.6 kDa
• AA Sequence: MASFVTEVLAHSGRLEKEDLGTRIS RLTRRVEEIKGEVCNMISKKYSEFL PSMQSAQGLITQVDKLSEDIDLLKS RIESEVRRDLHVSTGEFTDLKQQLE RDSVVLSLLKQLQEFSTAIEEYNCA LTEKKYVTGAQRLEEAQKCLKLLKS RKCFDLKILKSLSMELTIQKQNILY HLGEEWQKLIVWKFPPSKDTSSLES YLQTELHLYTEQSHKEEKTPMPPIS SVLLAFSVLGELHSKLKSFGQMLLK YILRPLASCPSLHAVIESQPNIVII RFESIMTNLEYPSPSEVFTKIRLVL EVLQKQLLDLPLDTDLENEKTSTVP LAEMLGDMIWEDLSECLIKNCLVYS IPTNSSKLQQYEEIIQSTEEFENAL KEMRFLKGDTTDLLKYARNINSHFA NKKCQDVIVAARNLMTSEIHNTVKI IPDSKINVPELPTPDEDNKLEVQKV SNTQYHEVMNLEPENTLDQHSFSLP TCRISESVKKLMELAYQTLLEATTS SDQCAVQLFYSVRNIFHLFHDVVPT YHKENLQKLPQLAAIHHNNCMYIAH HLLTLGHQFRLRLAPILCDGTATFV DLVPGFRRLGTECFLAQMRAQKGEL LERLSSARNFSNMDDEENYSAASKA VRQVLHQLKRLGIVWQDVLPVNIYC KAMGTLLNTAISEVIGKITALEDIS TEDGDRLYSLCKTVMDEGPQVFAPL SEESKNKKYQEEVPVYVPKWMPFKE LMMMLQASLQEIGDRWADGKGPLAA AFSSSEVKALIRALFQNTERRAAAL AKIKTRTRPLEQKLISEEDLAANDI LDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: ZW10 zw10 kinetochore protein [ Homo sapiens (human) ]
• Official Symbol: ZW10
• Synonyms: ZW10; ZW10, kinetochore associated, homolog (Drosophila); ZW10 (Drosophila) homolog, centromere/kinetochore protein; centromere/kinetochore protein zw10 homolog; KNTC1AP; zeste white 10 homolog; ZW10 homolog, centromere/kinetochore protein; HZW10; MGC149821
• Gene ID: 9183
• mRNA Refseq: NM_004724
• Protein Refseq: NP_004715
• MIM: 603954
• UniProt ID: O43264