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Active Recombinant HumanPK1 DAPK1 Protein, GST-His-tagged

Cat.No. : DAPK1-2335H
Product Overview : HumanPK1 (NM_004938, 1 a.a. - 363 a.a.) full-length recombinant protein with GST-His tag expressed in Sf9 cells.
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  • Gene Information
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Description : Death-associated protein kinase 1 is a positive mediator of gamma-interferon induced programmed cell death. DAPK1 encodes a structurally unique 160-kD calmodulin dependent serine-threonine kinase that carries 8 ankyrin repeats and 2 putative P-loop consensus sites. It is a tumor suppressor candidate. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2013]
Source : Insect Cells
Species : Human
Tag : GST-His
Form : Liquid
Bio-activity : 85 pmol/μg x min
Molecular Mass : 71.227 kDa
Applications : Functional Study
SDS-PAGE
Storage : Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
Concentration : 0.680 μg/μL
Storage Buffer : In 50 mM Tris-HCl, 100 mM NaCl, pH 8.0. (5 mM DTT, 4 mM reduced glutathione, 20% glycerol)
Gene Name : DAPK1 death-associated protein kinase 1 [ Homo sapiens ]
Official Symbol : DAPK1
Synonyms : DAPK1; death-associated protein kinase 1; DAPK; DAP kinase 1; DKFZp781I035;
Gene ID : 1612
mRNA Refseq : NM_004938
Protein Refseq : NP_004929
MIM : 600831
UniProt ID : P53355

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (6)

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What is the specific role of DAPK1 in apoptosis? 05/04/2022

DAPK1 plays an important role in apoptosis, which can promote the process of apoptosis.

How can diseases be treated by regulating DAPK1 levels? 08/16/2021

There are currently no drugs that directly regulate DAPK1 levels, but some DAPK1-related diseases can be treated by modulating its activity or regulating its expression.

What is the relationship of DAPK1 to other genes or proteins? 06/23/2020

DAPK1 has a complex relationship with other genes or proteins, and can interact with other genes or proteins to participate in a variety of biochemical reactions.

How to detect and analyze mutations in DAPK1? 05/12/2020

Mutations in DAPK1 can be detected and analyzed by methods such as whole-genome sequencing or target region sequencing to understand the impact of mutations on protein structure and function.

What are the mutation types of DAPK1? 04/20/2020

The types of mutations in DAPK1 include point mutations, insertions/deletions, duplications, etc., which may cause structural and functional abnormalities of the protein.

How to study the regulatory mechanism of DAPK1? 01/09/2020

Studying the regulatory mechanism of DAPK1 requires a comprehensive use of various experimental methods and techniques, such as gene knockout, transcriptome analysis, and protein-protein interactions.

Customer Reviews (3)

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Reviews
12/15/2022

    DAPK1 had the intended biological effect in the experiment.

    04/11/2022

      I've used many brands, but this one is one of my favorites.

      03/17/2022

        Good stability under different temperature and humidity conditions.

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