Recombinant Influenza A virus PA Protein (M1-R716)

• Cat.No.: PA-1538I
• Product Overview: Recombinant Influenza A virus RdRp(M1-R716 end) protein without tag was expressed in Insect cell

Specification

• Species: Influenza A virus
• Source: Insect Cells
• Tag: Non
• Protein Length: M1-R716
• Description: Plays an essential role in viral RNA transcription and replication by forming the heterotrimeric polymerase complex together with PB1 and PB2 subunits. The complex transcribes viral mRNAs by using a unique mechanism called cap-snatching. It consists in the hijacking and cleavage of host capped pre-mRNAs. These short capped RNAs are then used as primers for viral mRNAs. The PB2 subunit is responsible for the binding of the 5' cap of cellular pre-mRNAs which are subsequently cleaved after 10-13 nucleotides by the PA subunit that carries the endonuclease activity.
• Form: Liquid
• Endotoxin: < 0.01 EU/μg of the protein
• Purity: 90%
• Stability: Samples are stable for up to twelve months from date of receipt at -20 to -80 centigrade
• Storage: Store it under sterile conditions at -20 to -80 centigrade. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
• Storage Buffer: Supplied as sterile 50 mM Tris-HCl (pH7.5), 200 mM NaCl, 20% glycerol
• Shipping: It is shipped out with blue ice.

Gene Information

• Official Symbol: PA
• Synonyms: Polymerase acidic protein; PA; Polymerase acidic protein Automatic Annotation; EC:3.1.-.-; RNA-directed RNA polymerase subunit P2
• UniProt ID: G7WZE3