| Description : |
Middle East Respiratory Syndrome coronavirus (MERS-CoV) was initially isolated from a patient who was admitted to a private hospital in the Western part of the Kingdom of Saudi Arabia in 2012. Subsequently, MERS-CoV resulted in many sporadic cases, multiple intrafamilial transmission, and major outbreaks in healthcare settings. Of all the cases reported within the Kingdom of Saudi Arabia, 38% of the cases were primary, 45% were healthcare-associated infection, and 14% were household infections. The clinical spectrum of the MERS-CoV infection ranges from asymptomatic infections, mild or moderately symptomatic cases, and severe disease requiring intensive care unit admissions and may result in death. Within healthcare settings, transmissions of MERS-CoV are facilitated by overcrowding, poor infection control measures, unrecognized infections, and superspreader phenomenon. Currently, there is no approved therapy for MERS-CoV and there are no vaccines. |
| Source : |
HEK293 |
| Species : |
MERS-CoV |
| Tag : |
His-SUMO(N-ter) |
| Form : |
Powder |
| AA Sequence : |
MASPAAPRAVSFADNNDITNTNLSR GRGRNPKPRAAPNNTVSWYTGLTQH GKVPLTFPPGQGVPLNANSTPAQNA GYWRRQDRKINTGNGIKQLAPRWYF YYTGTGPEAALPFRAVKDGIVWVHE DGATDAPSTFGTRNPNNDSAIVTQF APGTKLPKNFHIEGTGGNSQSSSRA SSVSRNSSRSSSQGSRSGNSTRGTS PGPSGIGAVGGDLLYLDLLNRLQAL ESGKVKQSQPKVITKKDAAAAKNKM RHKRTSTKSFNMVQAFGLRGPGDLQ GNFGDLQLNKLGTEDPRWPQIAELA PTASAFMGMSQFKLTHQNNDDHGNP VYFLRYSGAIKLDPKNPNYNKWLEL LEQNIXAYKTFPKKEKKQKAPKEES TDQMSEPPKEQRVQGSITQRTRTRP SVQPGPMIDVNTD |
| Endotoxin : |
Endotoxin level is less than 0.1 EU/μg of the protein, as determined by the LAL test. |
| Purity : |
> 95% (by SDS-PAGE) |
| Applications : |
SDS-PAGE |
| Notes : |
For laboratory research only, not for drug, diagnostic or other use. |
| Storage : |
Lyophilized protein should be stored at -20°C. After reconstitution, aliquot and store at -20°C or -80°C for up to one month. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. |
| Storage Buffer : |
PBS (pH 7.4) |
| Reconstitution : |
It is recommended to reconstitute the lyophilized protein in sterile water to a concentration not less than 100 μg/mL and incubate the stock solution for at least 20 min at room temperature to make sure the protein is dissolved completely. |
