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Recombinant MERS-CoV S Protein, His-tagged

Cat.No. : S-016M
Product Overview : Recombinant MERS-CoV Spike S2 Subunit, fused to His-tag at C-terminus, was expressed in insect cell, and purified by using conventional chromatography techniques.
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Description : Spike protein S2: mediates fusion of the virion and cellular membranes by acting as a class I viral fusion protein. Under the current model, the protein has at least three conformational states: pre-fusion native state, pre-hairpin intermediate state, and post-fusion hairpin state. During viral and target cell membrane fusion, the coiled coil regions (heptad repeats) assume a trimer-of-hairpins structure, positioning the fusion peptide in close proximity to the C-terminal region of the ectodomain. The formation of this structure appears to drive apposition and subsequent fusion of viral and target cell membranes.
Source : Insect cells
Species : MERS-CoV
Tag : His
Form : Liquid
Molecular Mass : 60.7kDa
AA Sequence : SVPGEMRLASIAFNHPIQVDQLNSS YFKLSIPTNFSFGVTQEYIQTTIQK VTVDCKQYVCNGFQKCEQLLREYGQ FCSKINQALHGANLRQDDSVRNLFA SVKSSQSSPIIPGFGGDFNLTLLEP VSISTGSRSARSAIEDLLFDKVTIA DPGYMQGYDDCMQQGPASARDLICA QYVAGYKVLPPLMDVNMEAAYTSSL LGSIAGVGWTAGLSSFAAIPFAQSI FYRLNGVGITQQVLSENQKLIANKF NQALGAMQTGFTTTNEAFQKVQDAV NNNAQALSKLASELSNTFGAISASI GDIIQRLDVLEQDAQIDRLINGRLT TLNAFVAQQLVRSESAALSAQLAKD KVNECVKAQSKRSGFCGQGTHIVSF VVNAPNGLYFMHVGYYPSNHIEVVS AYGLCDAANPTNCIAPVNGYFIKTN NTRIVDEWSYTGSSFYAPEPITSLN TKYVAPQVTYQNISTNLPPPLLGNS TGIDFQDELDEFFKNVSTSIPNFGS LTQINTTLLDLTYEMLSLQQVVKAL NESYIDLKELGNYTYYNKWP
Endotoxin : < 1 EU/μg of protein (determined by LAL method)
Purity : > 85% by SDS-PAGE
Applications : SDS-PAGE
Storage : Can be stored at +2 to +8 centigrade for 1 week. For long term storage, aliquot and store at -20 to -95 centigrade. Avoid repeated freezing and thawing cycles.
Concentration : 0.25 mg/mL (determined by Absorbance at 280nm)
Storage Buffer : Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol
Official Symbol : S
Synonyms : Middle East respiratory syndrome coronavirus; Human betacoronavirus 2c EMC/2012; MERS-CoV; MERS; MERSCoV S2 P; Spike2 glycoprotein; S2 glycoprotein; S2; Spike S2 Subunit protein; S2 Subunit
UniProt ID : K0BRG7
Official Symbol : S
Synonyms : Middle East respiratory syndrome coronavirus; Human betacoronavirus 2c EMC/2012; MERS-CoV; MERS; MERSCoV S2 P; Spike2 glycoprotein; S2 glycoprotein; S2; Spike S2 Subunit protein; S2 Subunit
UniProt ID : K0BRG7

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Please let me know the sequence part you deleted or the whole aa region of this peptide 08/09/2023

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