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Recombinant Monkey EPCAM Protein, Fc-tagged, Alexa Fluor 647 conjugated

Cat.No. : EPCAM-186CAF647
Product Overview : A DNA sequence encoding the Monkey EPCAM [(Identical to the rhesus EPCAM (NP_001035118.1)] (Met1-Lys265) (Alexa Fluor 647 conjugated) was expressed with the Fc region of human IgG1 at the C-terminus.
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Source : HEK293
Species : Monkey
Tag : Fc
Form : Lyophilized
Molecular Mass : The recombinant cynomolgus EPCAM comprises 480 amino acids and has a calculated molecular mass of 54.1 kDa. The apparent molecular mass of the protein is approximately 58 kDa in SDS-PAGE.
Protein length : Met1-Lys265, 480
Endotoxin : < 1.0 EU/ μg of the protein as determined by the LAL method.
Purity : > 95 % as determined by SDS-PAGE
Characteristic : Disulfide-linked homodimer
Labeled with Alexa Fluor 647 via amines
Excitation = 650 nm
Emission = 668 nm
Stability : Samples are stable for up to 12 months from date of receipt at -70 centigrade.
Storage : Store it under sterile conditions at -70 centigrade. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Storage Buffer : Lyophilized from sterile PBS, pH7.4.
Gene Name : EPCAMepithelial cell adhesion molecule [Macaca mulatta(Rhesus monkey) ]
Official Symbol : EPCAM
Synonyms : EPCAM; Ep-CAM; TACSTD1; epithelial cell adhesion molecule; tumor-associated calcium signal transducer 1
Gene ID : 677680
mRNA Refseq : NM_001040029
Protein Refseq : NP_001035118
UniProt ID : Q1WER1

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (7)

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In which types of tissues is EpCAM predominantly expressed? 12/07/2022

EpCAM is highly expressed in epithelial tissues and some cancer cells.

How does EpCAM contribute to cell adhesion? 08/21/2022

It has a controversial role in cell adhesion, possibly contributing to both cell-cell adhesion and anti-adhesive properties.

What is the primary function of EpCAM in cells? 04/16/2022

EpCAM primarily functions in cell signaling, proliferation, and migration.

What role does EpCAM play in cancer progression? 03/19/2022

It often has a pro-tumorigenic role, promoting cancer cell proliferation, migration, and invasion.

How is EpCAM used as a biomarker in cancer diagnosis? 03/28/2021

EpCAM is used as a biomarker to detect and isolate circulating tumor cells.

What therapeutic strategies are being explored involving EpCAM? 11/23/2018

Strategies include developing EpCAM-targeted therapies for cancer treatment.

Are there known genetic alterations in EpCAM associated with specific health conditions? 11/07/2018

Genetic alterations in EpCAM are linked to some hereditary cancer syndromes.

Customer Reviews (3)

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02/13/2022

    Reliable for assays, satisfied customer.

    09/09/2019

      High-quality product, consistent results.

      04/03/2019

        Quick delivery, product as described.

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