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Recombinant Mouse Accn4 Protein, His-tagged

Cat.No. : Accn4-30M
Product Overview : Recombinant Mouse Accn4 Protein (Pro372-Cys539) with N-His tag was expressed in E. coli.
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  • Gene Information
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Description : Predicted to enable ligand-gated sodium channel activity. Acts upstream of or within behavioral fear response. Predicted to be located in membrane. Predicted to be integral component of membrane. Predicted to be integral component of plasma membrane. Is expressed in several structures, including adrenal gland; brain; gut; male reproductive gland or organ; and spinal cord mantle layer. Orthologous to human ASIC4 (acid sensing ion channel subunit family member 4).
Source : E. coli
Species : Mouse
Tag : N-His
Form : Freeze-dried powder
Molecular Mass : Predicted Molecular Mass: 22.4 kDa
Accurate Molecular Mass: 22 kDa
Protein length : Pro372-Cys539
Purity : > 90%
Applications : Positive Control; Immunogen; SDS-PAGE; WB.
Stability : The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 centigrade for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
Storage : Avoid repeated freeze/thaw cycles. Store at 2-8 centigrade for one month. Aliquot and store at -80 centigrade for 12 months.
Storage Buffer : PBS, pH7.4, containing 0.01% SKL, 1 mM DTT, 5% Trehalose and Proclin300.
Reconstitution : Reconstitute in sterile water to a concentration of 0.1-1.0 mg/mL. Do not vortex.
Gene Name : Accn4 amiloride-sensitive cation channel 4, pituitary [ Mus musculus (house mouse) ]
Official Symbol : Accn4
Synonyms : ACCN4; amiloride-sensitive cation channel 4, pituitary; amiloride-sensitive cation channel 4; acid-sensing ion channel 4; Asic4; BNAC4
Gene ID : 241118
mRNA Refseq : NM_183022
Protein Refseq : NP_898843
UniProt ID : Q7TNS7

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (10)

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Can the recombinant mouse ACCN4 protein be customized or modified to suit specific research needs? 05/13/2023

Creative BioMart offers customization or modification services for recombinant ACCN4 protein, such as adding tags or modifying the protein sequence.

Is there any discount for Recombinant Mouse ACCN4 Protein? 12/10/2022

For a limited duration, we have an exclusive holiday promotion where all our products are available with a 10% discount. Time is running out, so make sure to seize this opportunity and benefit from our discounted prices!

Can the Recombinant ACCN4 Protein be used for functional assays or protein-protein interaction studies? 07/19/2022

Yes, it can be used for various functional assays and protein-protein interaction studies. It is important to verify the suitability of the protein for specific assays and consult the literature or our technical support experts for recommended protocols or experimental conditions.

What is the involvement of ACCN4 protein in pathological conditions? 05/08/2022

ACCN4 has been implicated in several pathological conditions, including ischemic brain injury, neurodegenerative diseases, epilepsy, and chronic pain. Dysregulation of ACCN4 activity and expression levels may contribute to neuronal damage and hyperexcitability associated with these disorders. Thus, ACCN4 represents a potential therapeutic target for the development of novel treatments.

What is the cellular localization and tissue distribution of ACCN4 protein? 12/27/2021

It is predominantly localized to the plasma membrane of neurons, including those in the central and peripheral nervous systems. It exhibits a wide tissue distribution, with high expression levels observed in the brain, spinal cord, sensory ganglia, and certain regions of the cardiovascular and gastrointestinal systems.

Does the Recombinant ACCN4 Protein have any post-translational modifications? 06/14/2021

Depending on the expression system and purification method employed, the occurrence or non-occurrence of post-translational modifications in recombinant ACCN4 protein may differ. We offer tailored manufacturing of recombinant proteins, and you can specify your precise research needs when completing the online inquiry form.

I plan to buy ACCN4 protein, is there any discount for bulk? 12/11/2020

For every product listed on our website, Creative BioMart provides a bulk quotation. To obtain specific pricing details, kindly reach out to our sales representatives.

Does the His tag of Recombinant Mouse Accn4 Protein (Accn4-30M) affect the activity of the protein? 10/30/2020

The His tag enhances protein solubility and is employed for affinity purification, potentially influencing protein activity. If you have concerns about the tag's impact on protein activity, Creative BioMart also offers personalized tag-free ACCN4 protein services.

What is the price of recombinant mouse ACCN4 protein? 08/05/2017

The pricing of our products varies depending on the specific item. Typically, factors such as purity, quantity, and functional activity contribute to the determination of the price. To obtain information about pricing for specific products, please fill out an inquiry form, or feel free to reach out to our technical support team for consultation.

What is the recommended concentration and dilution for using Recombinant ACCN4 Protein in experiments? 06/24/2017

The recommended concentration and dilution of Recombinant ACCN4 Protein can vary depending on the specific experimental setup and applications. You can check the literature or seek technical support from our experts for recommended starting concentrations and provided protocols or guidelines.

Customer Reviews (3)

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Reviews
11/10/2022

    The Recombinant Mouse ACCN4 Protein was exactly what I needed for my experiments. It was easy to handle and produced consistent results.

    04/17/2018

      The Recombinant Mouse ACCN4 Protein was affordable and easy to order. The customer service team was helpful and responsive.

      04/13/2017

        I was impressed with the quality and purity of the recombinant ACCN4 protein. It performed exceptionally well in my experiments.

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