Recombinant Mouse ADAM12 Protein (206-706 aa), His-Myc-tagged

• Cat.No.: ADAM12-2799M
• Product Overview: Recombinant Mouse ADAM12 Protein (206-706 aa) is produced by Baculovirus expression system. This protein is fused with a 10xHis tag at the N-terminal and a Myc tag at the C-terminal. Research Area: Signal Transduction. Protein Description: Partial.

Specification

• Description: Involved in skeletal muscle regeneration, specifically at the onset of cell fusion. Also involved in macrophage-derived giant cells (MGC) and osteoclast formation from mononuclear precursors.
• Source: Baculovirus
• Species: Mouse
• Tag: His-Myc
• Form: Tris-based buffer,50% glycerol
• Molecular Mass: 58.4 kDa
• Protein length: 206-706 aa
• AA Sequence: ETLKMTKYVELVIVADNREFQRQGK DLEKVKQRLIEIANHVDKFYRPLNI RIVLVGVEVWNDIDKCSISQDPFTS LHEFLDWRKIKLLPRKSHDNAQLIS GVYFQGTTIGMAPIMSMCTAEQSGG VVMDHSDSPLGAAVTLAHELGHNFG MNHDTLERGCSCRMAAEKGGCIMNP STGFPFPMVFSSCSRKDLEASLEKG MGMCLFNLPEVKQAFGGRKCGNGYV EEGEECDCGEPEECTNRCCNATTCT LKPDAVCAHGQCCEDCQLKPPGTAC RGSSNSCDLPEFCTGTAPHCPANVY LHDGHPCQGVDGYCYNGICQTHEQQ CVTLWGPGAKPAPGICFERVNSAGD PYGNCGKDSKSAFAKCELRDAKCGK IQCQGGASRPVIGTNAVSIETNIPQ QEGGRILCRGTHVYLGDDMPDPGLV LAGTKCAEGKICLNRRCQNISVFGV HKCAMQCHGRGVCNNRKNCHCEAHW APPFCDKFGFGGSTDSGPIRQADNQ G
• Purity: > 90% as determined by SDS-PAGE.
• Notes: Repeated freezing and thawing is not recommended. Store working aliquots at 4 centigrade for up to one week.
• Storage: The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20 centigrade/-80 centigrade. The shelf life of lyophilized form is 12 months at -20 centigrade/-80 centigrade.
• Concentration: A hardcopy of COA will be sent along with the products. Please refer to it for detailed information.

Gene Information

• Gene Name: Adam12 a disintegrin and metallopeptidase domain 12 (meltrin alpha) [ Mus musculus ]
• Official Symbol: ADAM12
• Synonyms: ADAM12; ADAM 12; meltrin alpha; meltrin-alpha; Mltna; mKIAA4001
• Gene ID: 11489
• mRNA Refseq: NM_007400
• Protein Refseq: NP_031426
• UniProt ID: Q61824