Recombinant Mouse Adgre5 protein, His & T7-tagged

• Cat.No.: Adgre5-6923M
• Product Overview: Recombinant Mouse Adgre5 aa. (Ala32~Thr173 (Accession # Q9Z0M6)) fused with N-terminal His & T7 tag was produced in E. coli cells.

Specification

• Source: E. coli
• Species: Mouse
• Tag: His & T7
• Form: Freeze-dried powder
• Molecular Mass: Predicted Molecular Mass: 19.2kDa
• Protein length: Ala32~Thr173 (Accession # Q9Z0M6)
• Endotoxin: <1.0EU per 1ug (determined by the LAL method)
• Purity: >95%
• Characteristic: The isoelectric point is 6.3.
• Applications: SDS-PAGE; WB; ELISA; IP
• Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.
• Storage buffer: Supplied as lyophilized form in PBS, pH7.4, containing 5% sucrose, 0.01% sarcosyl.
• Reconstitution: Reconstitute in sterile PBS, pH7.2-pH7.4.

Gene Information

• Gene Name: Adgre5 adhesion G protein-coupled receptor E5 [ Mus musculus (house mouse) ]
• Official Symbol: Adgre5
• Synonyms: Adgre5; adhesion G protein-coupled receptor E5; Cd97; TM7LN1; AA409984; CD97 antigen; EGF-TM7 receptor
• Gene ID: 26364
• mRNA Refseq: NM_001163029.1
• Protein Refseq: NP_001156501.1
• UniProt ID: Q9Z0M6

Reviews

09/26/2021

Highly effective in detecting and measuring the activity of esterases in esterase assays.

07/27/2021

Shows excellent performance in detecting and measuring the activity of phosphatases in phosphatase assays.

Q&As

What are the downstream signaling pathways activated by ADGRE5 and how do they contribute to cellular processes?

ADGRE5 activates specific downstream signaling pathways, including [specific signaling cascades], which contribute to various cellular processes, such as [cell migration, invasion, or adhesion].

Can the expression or activity of ADGRE5 be modulated by pharmacological agents or genetic manipulation?

The expression or activity of ADGRE5 can be modulated by pharmacological agents that target [specific receptors or signaling pathways], or through genetic manipulation using [specific genetic tools or techniques].

Are there any known ligands or interacting partners that bind to the ADGRE5 protein and modulate its function?

ADGRE5 interacts with specific ligands or interacting partners, such as [specific molecules or cell surface receptors], leading to the modulation of its function.

Does ADGRE5 play a role in cell migration, invasion, or adhesion, and what are the underlying mechanisms?

ADGRE5 plays a role in cell migration, invasion, and adhesion through mechanisms involving [specific cellular processes or adhesion molecules].

What are the functional consequences of ADGRE5 activation or inhibition on cellular processes and disease progression?

Activation or inhibition of ADGRE5 has functional consequences on cellular processes and disease progression, impacting [specific cellular activities or disease outcomes].

Does ADGRE5 play a role in specific diseases or pathological conditions, and if so, what are the associated mechanisms?

ADGRE5 is implicated in specific diseases or pathological conditions, such as [specific cancer types or inflammatory disorders], where it contributes to [specific disease mechanisms or cellular dysregulation].

What is the tissue-specific expression pattern of the ADGRE5 protein across different organs and cell types?

The ADGRE5 protein exhibits a specific expression pattern across various tissues and cell types, with higher levels observed in [specific tissues or cell populations].

How is the expression of ADGRE5 regulated under normal physiological conditions and in response to specific stimuli?

Under normal physiological conditions, the expression of ADGRE5 is tightly regulated and can be modulated in response to specific stimuli, such as [specific cytokines or extracellular cues].

What is the impact of ADGRE5 deficiency or knockout on cell phenotypes or relevant biological processes?

Deficiency or knockout of ADGRE5 in cells leads to observable changes in cell phenotypes or altered biological processes, characterized by [specific cellular dysfunctions or functional impairments].

What is the subcellular localization and distribution pattern of ADGRE5 within cells or relevant cell types?

ADGRE5 exhibits a [specific subcellular localization pattern], with localization primarily observed in [specific cellular compartments, such as plasma membrane or endosomes].