Recombinant Mouse Adgrg1 Protein, MYC/DDK-tagged

• Cat.No.: Adgrg1-1048M
• Product Overview: Purified recombinant protein of full-length mouse adhesion G protein-coupled receptor G1 (Adgrg1), with C-terminal MYC/DDK tag, was expressed in HEK293T cells.

Specification

• Description: Ubiquitous expression in kidney adult (RPKM 93.7), ovary adult (RPKM 80.7) and 27 other tissues.
• Source: HEK293T
• Species: Mouse
• Tag: MYC/DDK
• Molecular Mass: 77.3 kDa
• Purity: >80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 µg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Adgrg1 adhesion G protein-coupled receptor G1 [ Mus musculus (house mouse) ]
• Official Symbol: Adgrg1
• Synonyms: Adgrg1; adhesion G protein-coupled receptor G1; Cyt28; Gpr56; TM7LN4; TM7XN1; adhesion G-protein coupled receptor G1; G-protein coupled receptor 56; secretin receptor; serpentine receptor cyt28
• Gene ID: 14766
• mRNA Refseq: NM_018882
• Protein Refseq: NP_061370
• UniProt ID: Q8K209

Reviews

06/09/2022

Highly stable and robust in biochemical assays.

09/10/2017

Demonstrates excellent specificity and sensitivity in detecting the target protein in fluorescence-based assays.

Q&As

What is the tissue-specific expression pattern of ADGRG1 and how is its expression regulated during development and in different cell types?

ADGRG1 exhibits a distinct tissue-specific expression pattern, regulated during development and in different cell types by [specific transcription factors or signaling pathways].

Can the function of ADGRG1 be modulated by pharmacological agents or genetic manipulation, and what are the consequences of such modulation?

The function of ADGRG1 can be modulated using pharmacological agents that target [specific receptors or downstream effectors], or through genetic manipulation using [specific genetic tools or techniques], resulting in [relevant consequences or functional changes].

Does ADGRG1 form homo-oligomers or hetero-oligomers with other proteins, and what are their functional implications?

ADGRG1 can form homo-oligomers or hetero-oligomers with other proteins, potentially influencing [specific cellular processes or signaling pathways] and providing functional implications.

What are the functional differences or similarities between ADGRG1 and other members of the adhesion G protein-coupled receptor (ADGR) family?

Comparisons between ADGRG1 and other members of the ADGR family can elucidate functional differences or similarities, providing a broader understanding of the roles of these receptors in [relevant physiological or pathological contexts].

Are there any known ligands or extracellular matrix components that interact with ADGRG1 and mediate its signaling?

ADGRG1 interacts with specific ligands or extracellular matrix components, such as [specific molecules or proteins], mediating its signaling events.

What are the physiological and pathological consequences of ADGRG1 knockout or overexpression in experimental models?

Knockout or overexpression of ADGRG1 in experimental models results in physiological and pathological consequences, including [specific phenotypic changes or disease manifestations], providing insights into its importance in [relevant biological contexts].

Does ADGRG1 play a role in specific cellular processes, such as cell adhesion, migration, or differentiation, and if so, what are the underlying mechanisms?

ADGRG1 is implicated in specific cellular processes, such as cell adhesion, migration, or differentiation, involving [specific molecular mechanisms or cellular machinery].

What are the downstream signaling pathways activated by ADGRG1 and how do they contribute to cellular functions and physiological processes?

Activation of ADGRG1 leads to the activation of downstream signaling pathways, such as [specific signaling cascades], which contribute to cellular functions and physiological processes including [relevant cellular processes or functional outcomes].

Are there any identified genetic variations or mutations in ADGRG1 associated with human diseases or phenotypic traits?

Identified genetic variations or mutations in ADGRG1 have been associated with human diseases or phenotypic traits, such as [specific disease conditions or clinical characteristics], providing insights into its role in [relevant disease mechanisms or phenotypic variations].

What is the subcellular localization of ADGRG1 and how does it impact its signaling and functional properties?

ADGRG1 exhibits a specific subcellular localization pattern, primarily localized to [specific cellular compartments, such as plasma membrane or endosomes], which impacts its signaling and functional properties.