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Recombinant Mouse Ager Protein, His-tagged

Cat.No. : Ager-712M
Product Overview : Recombinant Mouse Ager(Lys2~Lys228) fused with His tag at N-terminal was expressed in E. coli.
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Source : E. coli
Species : Mouse
Tag : His
Form : PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
Molecular Mass : 30.3kDa
Protein length : Lys2~Lys228
Endotoxin : <1.0EU per 1µg (determined by the LAL method)
Purity : > 98%
Applications : Positive Control; Immunogen; SDS-PAGE; WB.
If bio-activity of the protein is needed, please check active protein.
Stability : The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 centigrade for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
Storage : Avoid repeated freeze/thaw cycles. Store at 2-8 centigrade for one month. Aliquot and store at -80 centigrade for 12 months.
Reconstitution : Reconstitute in PBS or others.
Gene Name : Ager advanced glycosylation end product-specific receptor [ Mus musculus ]
Official Symbol : Ager
Synonyms : AGER; advanced glycosylation end product-specific receptor; advanced glycation end-products receptor; receptor for advanced glycosylation end products; advanced glycosylation end product-specific receptor variant 1; advanced glycosylation end product-specific receptor variant 2; advanced glycosylation end product-specific receptor variant 3; advanced glycosylation end product-specific receptor variant 4; advanced glycosylation end product-specific receptor variant 5; advanced glycosylation end product-specific receptor variant 6; RAGE;
Gene ID : 11596
mRNA Refseq : NM_007425
Protein Refseq : NP_031451
UniProt ID : Q62151

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (20)

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How does AGER affect bone health? 09/02/2022

AGER is involved in bone metabolism and might influence osteoporosis and bone diseases.

Are there diagnostic applications for AGER? 08/10/2022

AGER levels might serve as biomarkers for certain diseases, including diabetes.

How does AGER interact with AGEs? 07/05/2022

AGER binds AGEs, initiating signaling cascades linked to inflammation, oxidative stress, and tissue damage.

How is AGER implicated in skin aging? 05/30/2022

AGER contributes to skin aging through oxidative stress and collagen damage.

What is the AGER protein? 07/15/2021

AGER stands for "Advanced Glycosylation End-Product Specific Receptor," a cell surface receptor.

Can the AGER protein impact inflammation? 07/15/2021

Yes, AGER activation contributes to inflammation and immune responses.

How does AGER impact wound healing? 02/05/2021

AGER activation can impair wound healing through inflammation and oxidative stress.

How does AGER influence neurodegenerative diseases? 01/22/2021

AGER contributes to neuroinflammation and might play a role in neurodegeneration.

Can AGER influence kidney function? 12/06/2020

AGER contributes to diabetic nephropathy and kidney dysfunction.

How does the AGER protein interact with AGEs? 09/23/2020

AGER binds to AGEs, initiating cellular signaling pathways linked to inflammation and oxidative stress.

Can AGER influence lung health? 01/31/2020

AGER is implicated in lung diseases and inflammation, such as chronic obstructive pulmonary disease.

Are there therapeutic strategies targeting AGER? 06/09/2019

Researchers explore compounds that modulate AGER to mitigate its effects.

How is AGER involved in diabetic complications? 05/13/2019

AGER contributes to diabetic complications by promoting inflammation and tissue damage.

How is the AGER protein involved in research? 01/28/2019

AGER is studied for its implications in aging, diabetes, and various age-related diseases.

What is the function of the AGER protein? 07/25/2018

AGER plays a role in mediating cellular responses to advanced glycation end products (AGEs).

Are there dietary interventions for AGER-related effects? 10/05/2017

Consuming a low-AGE diet may help reduce AGER activation and its negative effects.

Can AGER impact immune responses? 06/29/2017

AGER activation affects immune cell functions and influences immune responses.

Does AGER affect cardiovascular health? 12/04/2016

AGER activation is linked to cardiovascular diseases, including atherosclerosis.

Are there other ligands for the AGER protein? 11/25/2016

Yes, besides AGEs, AGER interacts with other ligands like HMGB1 and β-amyloid.

Is AGER research ongoing? 11/02/2016

Yes, ongoing research aims to uncover new roles and therapeutic targets related to AGER.

Customer Reviews (5)

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Reviews
02/26/2022

    It's quality was evident in consistent results across replicates.

    08/13/2021

       Protein consistently upregulated the expression of tissue-specific markers.

      01/20/2020

         Gel electrophoresis bands displayed distinct separation, showcasing the product’s purity.

        06/22/2019

          It’s consistent outcomes supported reliable statistical analysis.

          01/11/2017

            Consistency and Compatibility Consistency in the product’s performance bolstered the credibility of our research findings.

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