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Recombinant Mouse Amotl2 Protein, Myc/DDK-tagged

Cat.No. : Amotl2-1614M
Product Overview : Purified recombinant protein of mouse full-length angiomotin-like 2 (Amotl2), with C-terminal MYC/DDK tag, expressed in HEK293T cells.
  • Specification
  • Gene Information
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Description : Regulates the translocation of phosphorylated SRC to peripheral cell-matrix adhesion sites. Required for proper architecture of actin filaments. Inhibits the Wnt/beta-catenin signaling pathway, probably by recruiting CTNNB1 to recycling endosomes and hence preventing its translocation to the nucleus. Participates in angiogenesis. May play a role in the polarity, proliferation and migration of endothelial cells. Selectively promotes FGF-induced MAPK activation through SRC.
Source : HEK293T
Species : Mouse
Tag : Myc/DDK
Molecular Mass : 85.3 kDa
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Stability : Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Storage : Store at -80 centigrade after receiving vials.
Concentration : >50 μg/mL as determined by microplate BCA method
Storage Buffer : 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Gene Name : Amotl2 angiomotin-like 2 [ Mus musculus (house mouse) ]
Official Symbol : Amotl2
Synonyms : Amotl2; angiomotin-like 2; Lc; MAS; Lccp; C79691; MASCOT; AW549739; mKIAA0989; angiomotin-like protein 2; Leman coiled-coil protein
Gene ID : 56332
mRNA Refseq : NM_019764
Protein Refseq : NP_062738
UniProt ID : Q8K371

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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