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| Cat.No.: | Antxr2-45M |
| Product Overview: | Recombinant mouse ANTXR2, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques. |
| Description: | ANTXR2, also known as anthrax toxin receptor 2, is a widely expressed anthrax toxin receptor family protein. The main functional domain of this protein is an extracellular integrinlike von Willebrand factor type A (VWA) domain with a metal ion dependent adhesion site, through which it adheres selectively to collagen type IV and laminin. This protein and the related protein ATR/TEM8 serve as receptors for the protective antigen of Bacillus anthracis. |
| Source: | Insect cells |
| Species: | Mouse |
| Tag: | His tag |
| Form: | Liquid. In Phosphate Buffered Saline (pH 7.4) containing 10% glycerol. |
| Molecular Mass: | 31.9kDa (295aa)28-40KDa (SDS–PAGE under reducing conditions.) |
| AA Sequence: | QAQEQPSCKK AFDLYFVLDK SGSVANNWIE IYNFVHQLTE RFVSPEMRLS FIVFSSQATI ILPLTGDRYK IGKGLEDLKA VKPVGETYIH EGLKLANEQI QNAGGLKASS IIIALTDGKL DGLVPSYAEN EAKKSRSLGA SVYCVGVLDF EQAQLERIAD SKDQVFPVKG GFQALKGIIN SILAQSCTEI LELSPSSVCV GEKFQVVLTG RAVTSISHDG SVLCTFTANS TYTKSEKPVS IQPSSILCPA PVLNKDGETL EVSISYNDGK SAVSRSLTIT ATECTNGLEH HHHHH |
| Endotoxin: | < 1.0 EU per 1 microgram of protein (determined by LAL method) |
| Purity: | >95% by SDS - PAGE |
| Storage: | Can be stored at +4centigrade short term (1-2 weeks). For long term storage, aliquot and store at -20Centigrade or -70Centigrade. Avoid repeated freezing and thawing cycles. |
| Concentration: | 0.5mg/ml (determined by Absorbance at 280nm) |
| Gene Name: | Antxr2 anthrax toxin receptor 2 [ Mus musculus ] |
| Official Symbol: | Antxr2 |
| Synonyms: | ANTXR2; anthrax toxin receptor 2; CMG2; CMG-2; cI-35; AW561899; 2310046B19Rik; |
| Gene ID: | 71914 |
| mRNA Refseq: | NM_133738 |
| Protein Refseq: | NP_598499 |
| MIM: | |
| UniProt ID: | |
| Function: | metal ion binding; receptor activity; |
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