Recombinant Mouse Api5 Protein, MYC/DDK-tagged

• Cat.No.: Api5-628M
• Product Overview: Purified recombinant protein of full-length mouse apoptosis inhibitor 5 (Api5), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Species: Mouse
• Source: HEK293
• Tag: DDK&Myc
• Description: Antiapoptotic factor that may have a role in protein assembly. Negatively regulates ACIN1. By binding to ACIN1, it suppresses ACIN1 cleavage from CASP3 and ACIN1-mediated DNA fragmentation. Also known to efficiently suppress E2F1-induced apoptosis.
• Molecular Mass: 56.8 kDa
• Purity: >80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Api5 apoptosis inhibitor 5 [ Mus musculus (house mouse) ]
• Official Symbol: Api5
• Synonyms: Api5; apoptosis inhibitor 5; API-5; AAC-11; AI196452; apoptosis inhibitor 5; apoptosis inhibitory protein 5
• Gene ID: 11800
• mRNA Refseq: NM_007466
• Protein Refseq: NP_031492
• UniProt ID: O35841