Recombinant Mouse Aplf Protein, Myc/DDK-tagged
Cat.No. : | Aplf-1661M |
Product Overview : | Purified recombinant protein of mouse full-length aprataxin and PNKP like factor (Aplf), with C-terminal MYC/DDK tag, expressed in HEK293T cells. |
- Specification
- Gene Information
- Related Products
Description : | Nuclease involved in single-strand and double-strand DNA break repair. Recruited to sites of DNA damage through interaction with poly(ADP-ribose), a polymeric post-translational modification synthesized transiently at sites of chromosomal damage to accelerate DNA strand break repair reactions. Displays apurinic-apyrimidinic (AP) endonuclease and 3'-5' exonuclease activities in vitro. Also able to introduce nicks at hydroxyuracil and other types of pyrimidine base damage. Together with PARP3, promotes the retention of the LIG4-XRCC4 complex on chromatin and accelerate DNA ligation during non-homologous end-joining (NHEJ). |
Source : | HEK293T |
Species : | Mouse |
Tag : | Myc/DDK |
Molecular Mass : | 55.4 kDa |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Stability : | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
Storage : | Store at -80 centigrade after receiving vials. |
Concentration : | >50 μg/mL as determined by microplate BCA method |
Storage Buffer : | 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol. |
Gene Name : | Aplf aprataxin and PNKP like factor [ Mus musculus (house mouse) ] |
Official Symbol : | Aplf |
Synonyms : | APLF; aprataxin and PNKP like factor; aprataxin and PNK-like factor; apurinic-apyrimidinic endonuclease APLF; AI452191; 2010301N04Rik |
Gene ID : | 72103 |
mRNA Refseq : | NM_001170489 |
Protein Refseq : | NP_001163960 |
UniProt ID : | Q9D842 |
Products Types
◆ Recombinant Protein | ||
APLF-2483H | Recombinant Human APLF Protein, His (Fc)-Avi-tagged | +Inquiry |
APLF-622M | Recombinant Mouse APLF Protein, His (Fc)-Avi-tagged | +Inquiry |
APLF-12H | Recombinant Human APLF protein, DDK-tagged | +Inquiry |
APLF-5481C | Recombinant Chicken APLF | +Inquiry |
APLF-1773M | Recombinant Mouse APLF Protein | +Inquiry |
◆ Lysates | ||
APLF-8793HCL | Recombinant Human APLF 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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