Recombinant Mouse Arhgef15 Protein, Myc/DDK-tagged

• Cat.No.: Arhgef15-1692M
• Product Overview: Purified recombinant protein of mouse full-length Rho guanine nucleotide exchange factor (GEF) 15 (Arhgef15), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Description: Specific GEF for RhoA activation. Does not activate RAC1 or CDC42. Regulates vascular smooth muscle contractility. Negatively regulates excitatory synapse development by suppressing the synapse-promoting activity of EPHB2.
• Source: HEK293T
• Species: Mouse
• Tag: Myc/DDK
• Molecular Mass: 92.9 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Arhgef15 Rho guanine nucleotide exchange factor (GEF) 15 [ Mus musculus (house mouse) ]
• Official Symbol: Arhgef15
• Synonyms: ARHGEF15; Rho guanine nucleotide exchange factor (GEF) 15; rho guanine nucleotide exchange factor 15; ephexin-5; E5; D130071N09; D530030K12Rik; RP23-396M19.6; MGC102247; MGC144141; MGC144142
• Gene ID: 442801
• mRNA Refseq: NM_177566
• Protein Refseq: NP_808234
• UniProt ID: Q5FWH6