Recombinant Mouse Arid3a Protein, Myc/DDK-tagged

• Cat.No.: Arid3a-1698M
• Product Overview: Purified recombinant protein of mouse full-length AT rich interactive domain 3A (BRIGHT-like) (Arid3a), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Description: Transcription factor involved in B-cell differentiation. Binds a VH promoter proximal site necessary for induced mu-heavy-chain transcription. Binds the minor groove of a restricted ATC sequence that is sufficient for nuclear matrix association. This sequence motif is present in matrix-associating regions (MARS) proximal to the promoter and flanking E mu. Activates E mu-driven transcription by binding these sites. May be involved in the control of cell cycle progression by the RB1/E2F1 pathway.
• Source: HEK293T
• Species: Mouse
• Tag: Myc/DDK
• Molecular Mass: 63.9 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Arid3a AT rich interactive domain 3A (BRIGHT-like) [ Mus musculus (house mouse) ]
• Official Symbol: Arid3a
• Synonyms: ARID3A; AT rich interactive domain 3A (BRIGHT-like); AT-rich interactive domain-containing protein 3A; dead ringer homolog 1; dead ringer-like protein 1; ARID domain-containing protein 3A; B-cell regulator of IgH transcription; AT rich interactive domain 3A (Bright like); Dri1; Dril1; Bright
• Gene ID: 13496
• mRNA Refseq: NM_007880
• Protein Refseq: NP_031906
• UniProt ID: Q62431