Recombinant Mouse Arx Protein, MYC/DDK-tagged


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Recombinant Mouse Arx Protein, MYC/DDK-tagged

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Cat.No. : Arx-652M
Product Overview : Purified recombinant protein of full-length mouse aristaless related homeobox (Arx), with C-terminal MYC/DDK tag, expressed in HEK293T cells.
Description : This gene encodes a transcription factor that plays an important role in the development of forebrain. Male mice lacking this gene have smaller brains, olfactory bulbs and testes, and die within half a day after birth. Mice lacking this gene specifically in ganglionic eminence-derived neurons, including cortical interneurons, develop seizures. Mutations in this gene have been demonstrated to cause mouse phenotypes resembling human X-linked lissencephaly and cognitive disability with epilepsy. Alternative splicing results in multiple transcript variants.
Source : HEK293T
Species : Mouse
Molecular Mass : 58.9 kDa
Purity : >80% as determined by SDS-PAGE and Coomassie blue staining
Stability : Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Storage : Store at -80 centigrade after receiving vials.
Concentration : >50 μg/mL as determined by microplate BCA method
Storage Buffer : 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Gene Name : Arx aristaless related homeobox [ Mus musculus (house mouse) ]
Official Symbol : Arx
Synonyms : Arx; aristaless related homeobox; Arx1; homeobox protein ARX
Gene ID : 11878
mRNA Refseq : NM_007492
Protein Refseq : NP_031518
UniProt ID : O35085
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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