Recombinant Mouse Ascc2 Protein, Myc/DDK-tagged

• Cat.No.: Ascc2-1738M
• Product Overview: Purified recombinant protein of mouse full-length activating signal cointegrator 1 complex subunit 2 (Ascc2), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Species: Mouse
• Source: HEK293
• Tag: DDK&Myc
• Description: Plays a role in DNA damage repair as component of the ASCC complex. Recruits ASCC3 and ALKBH3 to sites of DNA damage by binding to polyubiquitinated proteins that have 'Lys-63'-linked polyubiquitin chains. Part of the ASC-1 complex that enhances NF-kappa-B, SRF and AP1 transactivation.
• Molecular Mass: 85.7 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Ascc2 activating signal cointegrator 1 complex subunit 2 [ Mus musculus (house mouse) ]
• Official Symbol: Ascc2
• Synonyms: ASCC2; activating signal cointegrator 1 complex subunit 2; ASC-1 complex subunit P100; trip4 complex subunit p100; AI482016; ASC1p100; AW046480; RP23-280J3.3; 1700011I11Rik; 2610034L15Rik; FLJ21588
• Gene ID: 75452
• mRNA Refseq: NM_029291
• Protein Refseq: NP_083567
• UniProt ID: Q91WR3