Recombinant Mouse Aspa Protein, MYC/DDK-tagged Aspa-531M

Recombinant Mouse Aspa Protein, MYC/DDK-tagged

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Recombinant Mouse Aspa Protein, MYC/DDK-tagged

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Cat.No. : Aspa-531M
Product Overview : Purified recombinant protein of full-length mouse aspartoacylase (Aspa), with C-terminal MYC/DDK tag, expressed in HEK293T cells.
Description : This gene encodes an enzyme that deacteylates N-acetyl-L-aspartic acid (NAA) in the brain to yield acetate and L-aspartate. In humans, alterations in neuronal NAA concentration are associated with many neurodegenerative diseases (decrease associated with epilepsy, multiple sclerosis, myotrophic lateral sclerosis, and Alzheimer's disease; increase associated with Canavan disease). In mouse, mutations in this gene, which cause accumulation of NAA, result in demyelination and spongy degeneration in the CNS and serve as a pathophysiological model for Canavan disease.
Source : HEK293T
Species : Mouse
Tag : MYC/DDK
Molecular Mass : 35.3 kDa
Purity : >80% as determined by SDS-PAGE and Coomassie blue staining
Stability : Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Storage : Store at -80 centigrade after receiving vials.
Concentration : >50 μg/mL as determined by microplate BCA method
Storage Buffer : 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Gene Name : Aspa aspartoacylase [ Mus musculus (house mouse) ]
Official Symbol : Aspa
Synonyms : Aspa; aspartoacylase; Acy2; nur7; Acy-2; aspartoacylase; aminoacylase-2; aspartoacylase (aminoacylase) 2; EC 3.5.1.15
Gene ID : 11484
mRNA Refseq : NM_023113
Protein Refseq : NP_075602
UniProt ID : Q8R3P0

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