Recombinant Mouse Atp2a1 Protein, MYC/DDK-tagged

Cat.No. : Atp2a1-666M
Product Overview : Purified recombinant protein of full-length mouse ATPase, Ca++ transporting, cardiac muscle, fast twitch 1 (Atp2a1), with C-terminal MYC/DDK tag, expressed in HEK293T cells.
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Description : Restricted expression toward mammary gland adult (RPKM 780.9).
Source : HEK293T
Species : Mouse
Tag : Myc&DDK
Molecular Mass : 109.4 kDa
Purity : >80% as determined by SDS-PAGE and Coomassie blue staining
Stability : Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Storage : Store at -80 centigrade after receiving vials.
Concentration : >50 μg/mL as determined by microplate BCA method
Storage Buffer : 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Gene Name : Atp2a1 ATPase, Ca++ transporting, cardiac muscle, fast twitch 1 [ Mus musculus (house mouse) ]
Official Symbol : Atp2a1
Synonyms : Atp2a1; ATPase, Ca++ transporting, cardiac muscle, fast twitch 1; SERCA1; sarcoplasmic/endoplasmic reticulum calcium ATPase 1; SR Ca(2+)-ATPase 1; calcium pump 1; calcium-transporting ATPase sarcoplasmic reticulum type, fast twitch skeletal muscle isoform; endoplasmic reticulum class 1/2 Ca(2+) ATPase; EC 7.2.2.10
Gene ID : 11937
mRNA Refseq : NM_007504
Protein Refseq : NP_031530
UniProt ID : Q8R429

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Customer Reviews (3)

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Reviews
04/09/2022

    It is noteworthy that the results of multiple experiments were highly consistent and reproducible.

    12/19/2021

      The catalytic activity of ATP2A1 is very excellent, not only the catalytic effect is remarkable, but also has high selectivity, and its performance is impressive.

      06/28/2019

        They produced ATP2A1 with high purity and accurate experimental results.

        Q&As (6)

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        Are the expression and function of ATP2Arecombinant protein regulated in cardiomyocytes? 08/25/2022

        Yes, the expression and function of ATP2A1 recombinant protein in cardiomyocytes are regulated by different regulatory mechanisms, such as endogenous hormones and signaling pathways.

        What other proteins does the recombinant ATP2Aprotein interact with? 07/04/2022

        The recombinant ATP2A1 protein interacts with other proteins of the sarcoplasmic reticulum, such as calsequestrin and phospholamban, to regulate muscle contraction.

        Does the recombinant ATP2 Aprotein have drug target potential? 02/07/2021

        The ATP2A1 recombinant protein can be used as a drug target because it plays an important role in regulating muscle and cardiomyocyte function. However, there are no clinically applicable drugs targeting ATP2A1.

        What is the role of ATP2 Arecombinant protein in cardiovascular disease? 04/18/2020

        Impairment of the normal function of ATP2A1 recombinant protein in cardiomyocytes may contribute to the development of cardiovascular diseases, such as reduced myocardial contractility and heart failure.

        How does recombinant ATP2A protein play a role in muscle diseases? 02/28/2020

        Mutations in the ATP2A1 recombinant protein may cause calcium leakage and abnormal muscle contraction, leading to muscle diseases.

        How does the recombinant ATP2A protein interact with specific drugs? 10/27/2019

        Certain drugs can affect the function of the recombinant ATP2A1 protein, such as calcium antagonists and cardiac agonists. These drugs regulate calcium homeostasis in muscle and cardiomyocytes.

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