Recombinant Mouse Atxn1 Protein, Myc/DDK-tagged

• Cat.No.: Atxn1-1782M
• Product Overview: Purified recombinant protein of mouse full-length ataxin 1 (Atxn1), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Species: Mouse
• Source: HEK293
• Tag: DDK&Myc
• Description: Chromatin-binding factor that repress Notch signaling in the absence of Notch intracellular domain by acting as a CBF1 corepressor. Binds to the HEY promoter and might assist, along with NCOR2, RBPJ-mediated repression. May be involved in RNA metabolism. In concert with CIC and ATXN1L, involved in brain development.
• Molecular Mass: 83.8 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Atxn1 ataxin 1 [ Mus musculus (house mouse) ]
• Official Symbol: Atxn1
• Synonyms: ATXN1; ataxin 1; ataxin-1; spinocerebellar ataxia 1 homolog; Atx1; Sca1; C85907; Gm10786; 2900016G23Rik; ENSMUSG00000074917
• Gene ID: 20238
• mRNA Refseq: NM_009124
• Protein Refseq: NP_033150
• UniProt ID: P54254