Recombinant Mouse B2m & Fcgrt protein, His-Avi-tagged

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Recombinant Mouse B2m & Fcgrt protein, His-Avi-tagged

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Cat.No. : B2m & Fcgrt-054M
Product Overview : Mouse FcRn is expressed from mammalian with a His tag and Avi Tag at the C-terminal. . It contains Ser22-Ser297(FCGRT)& Ile21-Met119(B2M) .
Description : The neonatal Fc receptor (FCRN) is an approximately 45 kDa transmembrane glycoprotein with structural homology to MHC class I proteins. It is widely expressed in endothelial and epithelial cells and plays an important role in IgG homeostasis and antigen presentation by dendritic cells.FCGRT & B2M heterodimer protein (FcRn complex) consist of two subunits: p51, and p14 , and forms an MHC class I-like heterodimer.
Source : HEK293
Species : Mouse
Tag : His-Avi
Form : Supplied as 0.22um filtered solution in PBS (pH 7.4).
Molecular Mass : The protein has a predicted MW of 47.1 kDa same as Bis-Tris PAGE result.
Protein length : It contains Ser22-Ser297(FCGRT)& Ile21-Met119(B2M).
Endotoxin : Less than 0.01EU per ug by the LAL method.
Purity : > 95% as determined by Bis-Tris PAGE
Storage : The product should be stored at -70°C. Please do not repeated freeze-thaw cycles.
Reconstitution : It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4ºC before opening to recover the entire contents.
Tris-Bis PAGE :

HPLC data :

Gene Name : B2m beta-2 microglobulin [ Mus musculus (house mouse) ]
Official Symbol : B2m ; Fcgrt
Synonyms : FcRn alpha chain;alpha-chain; Fc fragment of IgG, receptor, transporter, alpha; FCGRT; FCRN; FCRNimmunoglobulin receptor, intestinal, heavy chain; IgG Fc fragment receptor transporter alpha chain; IgG receptor FcRn large subunit p51; major histocompatibility complex class I-like Fc receptor; Neonatal Fc receptor; neonatal Fc-receptor for Ig
Gene ID : 12010
mRNA Refseq : NM_009735.3
Protein Refseq : NP_033865.2
UniProt ID : P01887

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