Recombinant Mouse B2m & Fcgrt protein, His-Avi-tagged

• Cat.No.: B2m & Fcgrt-054M
• Product Overview: Mouse FcRn is expressed from mammalian with a His tag and Avi Tag at the C-terminal. . It contains Ser22-Ser297(FCGRT)& Ile21-Met119(B2M) .

Specification

• Species: Mouse
• Source: HEK293
• Tag: Avi&His
• Protein Length: It contains Ser22-Ser297(FCGRT)& Ile21-Met119(B2M).
• Description: The neonatal Fc receptor (FCRN) is an approximately 45 kDa transmembrane glycoprotein with structural homology to MHC class I proteins. It is widely expressed in endothelial and epithelial cells and plays an important role in IgG homeostasis and antigen presentation by dendritic cells.FCGRT & B2M heterodimer protein (FcRn complex) consist of two subunits: p51, and p14 , and forms an MHC class I-like heterodimer.
• Form: Supplied as 0.22um filtered solution in PBS (pH 7.4).
• Molecular Mass: The protein has a predicted MW of 47.1 kDa same as Bis-Tris PAGE result.
• Endotoxin: Less than 0.01EU per ug by the LAL method.
• Purity: > 95% as determined by Bis-Tris PAGE
• Storage: The product should be stored at -70°C. Please do not repeated freeze-thaw cycles.
• Reconstitution: It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4℃ before opening to recover the entire contents.

Gene Information

• Gene Name: B2m beta-2 microglobulin [ Mus musculus (house mouse) ]
• Official Symbol: B2m ; Fcgrt
• Synonyms: FcRn alpha chain;alpha-chain; Fc fragment of IgG, receptor, transporter, alpha; FCGRT; FCRN; FCRNimmunoglobulin receptor, intestinal, heavy chain; IgG Fc fragment receptor transporter alpha chain; IgG receptor FcRn large subunit p51; major histocompatibility complex class I-like Fc receptor; Neonatal Fc receptor; neonatal Fc-receptor for Ig
• Gene ID: 12010
• mRNA Refseq: NM_009735.3
• Protein Refseq: NP_033865.2
• UniProt ID: P01887