Recombinant Mouse B4galt5 Protein, Myc/DDK-tagged

• Cat.No.: B4galt5-1810M
• Product Overview: Purified recombinant protein of Mouse UDP-Gal:betaGlcNAc beta 1,4-galactosyltransferase, polypeptide 5 (B4galt5), full length, with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Description: Catalyzes the synthesis of lactosylceramide (LacCer) via the transfer of galactose from UDP-galactose to glucosylceramide (GlcCer). LacCer is the starting point in the biosynthesis of all gangliosides (membrane-bound glycosphingolipids) which play pivotal roles in the CNS including neuronal maturation and axonal and myelin formation. Plays a role in the glycosylation of BMPR1A and regulation of its protein stability. Essential for extraembryonic development during early embryogenesis.
• Source: HEK293T
• Species: Mouse
• Tag: Myc/DDK
• Molecular Mass: 45.3 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris-HCl, pH 7.3, 100 mM glycine, 10% glycerol

Gene Information

• Gene Name: B4galt5 UDP-Gal:betaGlcNAc beta 1,4-galactosyltransferase, polypeptide 5 [ Mus musculus (house mouse) ]
• Official Symbol: B4galt5
• Synonyms: B4GALT5; UDP-Gal:betaGlcNAc beta 1,4-galactosyltransferase, polypeptide 5; beta-1,4-galactosyltransferase 5; b4Gal-T5; beta4Gal-T5; beta-1,4-GalT II; beta-1,4-GalTase 5; beta-1,4-galactosyltransferase V; UDP-Gal:beta-GlcNAc beta-1,4-galactosyltransferase 5; UDP-galactose:beta-N-acetylglucosamine beta-1,4-galactosyltransferase 5; AW049941; AW539721; 9430078I07Rik
• Gene ID: 56336
• mRNA Refseq: NM_019835
• Protein Refseq: NP_062809
• UniProt ID: Q9JMK0