Recombinant Full Length Mouse Bcl2 Protein, His tagged

• Cat.No.: Bcl2-3582M
• Product Overview: Recombinant Full Length Mouse Bcl2 Protein with His tag was expreessed in E.coli.

Specification

• Species: Mouse
• Source: E.coli
• Tag: His
• Protein Length: 1-236 aa
• Description: This gene encodes a member of the B cell lymphoma 2 protein family. Members of this family regulate cell death in multiple cell types and can have either proapoptotic or antiapoptotic activities. The protein encoded by this gene inhibits mitochondrial-mediated apoptosis. This protein is an integral outer mitochondrial membrane protein that functions as part of signaling pathway that controls mitochondrial permeability in response to apoptotic stimuli. This protein may also play a role in neuron cell survival and autophagy. Abnormal expression and chromosomal translocations of this gene are associated with cancer progression in numerous tissues. Alternate splicing results in multiple transcript variants.
• Form: Sterile 20mM Tris, pH8.0, 200mM NaCl, 0.1%SKL
• Molecular Mass: 29 kDa
• AASequence: MHHHHHHHHHHHHDYKDDDDKMAQAGRTGYDNREIVMKYIHYKLSQRGYEWDAGDADAAPLGAAPTPGIFSFQPESNPMPAVHRDMAARTSPLRPLVATAGPALSPVPPVVHLTLRRAGDDFSRRYRRDFAEMSSQLHLTPFTARGRFATVVEELFRDGVNWGRIVAFFEFGGVMCVESVNREMSPLVDNIALWMTEYLNRHLHTWIQDNGGWDAFVELYGPSMRPLFDFSWLSLKTLLSLALVGACITLGAYLGHK
• Purity: >80% by SDS-PAGE
• Storage: Store it under sterile conditions at -20 to -80 centigrade. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
• Concentration: 0.43 mg/mL by BCA

Gene Information

• Gene Name: Bcl2 B cell leukemia/lymphoma 2 [ Mus musculus ]
• Official Symbol: Bcl2
• Synonyms: BCL2; B cell leukemia/lymphoma 2; apoptosis regulator Bcl-2; B-cell leukemia/lymphoma 2; Bcl-2; AW986256; C430015F12Rik; D630044D05Rik; D830018M01Rik
• Gene ID: 12043
• mRNA Refseq: NM_009741
• Protein Refseq: NP_033871