Recombinant Mouse Bdnf protein, His & GST-tagged
Cat.No. : | Bdnf-550M |
Product Overview : | Recombinant Mouse Bdnf (P21237) aa. (Glu139~Arg249) fused with N-terminal His & GST tag was produced in E. coli cells. |
- Specification
- Gene Information
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Description : | The protein encoded by this gene is a member of the nerve growth factor family. It is involved in the growth, differentiation and survival of specific types of developing neurons both in the central nervous system (CNS) and the peripheral nervous system. It is also involved in regulating synaptic plasticity in the CNS. Expression of a similar gene in human is reduced in both Alzheimer's and Huntington disease patients. Alternative splicing results in multiple transcript variants encoding different isoforms that may undergo similar processing to generate mature protein. |
Source : | E. coli |
Species : | Mouse |
Tag : | His & GST |
Form : | Freeze-dried powder |
Molecular Mass : | 43kDa as determined by SDS-PAGE reducing conditions |
Protein length : | Glu139~Arg249 |
Endotoxin : | <1.0EU per 1µg (determined by the LAL method) |
Purity : | > 92% |
Characteristic : | The isoelectric point is 8.5. |
Applications : | SDS-PAGE; WB; ELISA; IP; CoIP; ReporterAssays; Purification; Amine Reactive Labeling. |
Stability : | The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition. |
Storage : | Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months. |
Concentration : | 200µg/mL |
Storage buffer : | 20mM Tris, 150mM NaCl, pH8.0, containing 1mM EDTA, 1mM DTT, 0.01% sarcosyl, 5%Trehalose and Proclin300. |
Reconstitution : | Reconstitute in 20mM Tris, 150mM NaCl (pH8.0) to a concentration of 0.1-1.0 mg/mL. Do not vortex. |
Gene Name : | Bdnf brain derived neurotrophic factor [ Mus musculus (house mouse) ] |
Official Symbol : | Bdnf |
Synonyms : | Bdnf; brain derived neurotrophic factor; brain-derived neurotrophic factor |
Gene ID : | 12064 |
mRNA Refseq : | NM_001048139.1 |
Protein Refseq : | NP_001041604.1 |
UniProt ID : | P21237 |
Products Types
◆ Recombinant Protein | ||
Bdnf-310M | Recombinant Mouse Bdnf Protein, His-tagged | +Inquiry |
Bdnf-703M | Recombinant Mouse Bdnf Protein, MYC/DDK-tagged | +Inquiry |
BDNF-312H | Recombinant Human BDNF Protein, His-tagged | +Inquiry |
BDNF-311C | Recombinant Cattle BDNF Protein, His-tagged | +Inquiry |
BDNF-01H | Recombinant Active Human BDNF Protein, His-tagged | +Inquiry |
◆ Lysates | ||
BDNF-001MCL | Recombinant Mouse BDNF cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (5)
Ask a questionBDNF levels can be measured through blood tests or cerebrospinal fluid analysis, providing insights into the protein's concentration in the body.
BDNF deficiency has been linked to conditions such as Alzheimer's disease, Parkinson's disease, and depression.
While there are no direct BDNF medications, certain drugs and treatments aim to enhance BDNF levels indirectly, offering potential therapeutic benefits.
Physical exercise has been shown to increase BDNF production, suggesting that exercise could be used as a non-pharmacological intervention to support neurological health.
BDNF is crucial for synaptic plasticity, influencing the strength and efficacy of connections between neurons, which is vital for learning and memory processes.
Customer Reviews (3)
Write a reviewThe BDNF protein is carefully characterized, and its functional properties are well-documented.
With its high purity and bioactivity, BDNF protein ensures reliable and consistent results in a wide range of experimental applications.
The BDNF protein is of exceptional quality and is perfectly suited to meet the experimental needs of researchers.
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