Recombinant Mouse Brms1 Protein, MYC/DDK-tagged Brms1-328M

Recombinant Mouse Brms1 Protein, MYC/DDK-tagged

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Recombinant Mouse Brms1 Protein, MYC/DDK-tagged

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Cat.No. : Brms1-328M
Product Overview : Purified recombinant protein of full-length mouse breast cancer metastasis-suppressor 1 (cDNA clone MGC:6927 IMAGE:2811430), complete cds, with C-terminal MYC/DDK tag, expressed in HEK293T cells.
Description : Transcriptional repressor. Down-regulates transcription activation by NF-kappa-B by promoting the deacetylation of RELA at 'Lys-310'. Promotes HDAC1 binding to promoter regions. Down-regulates expression of anti-apoptotic genes that are controlled by NF-kappa-B. Promotes apoptosis in cells that have inadequate adherence to a substrate, a process called anoikis, and may thereby inhibit metastasis.
Source : HEK293T
Species : Mouse
Tag : MYC/DDK
Molecular Mass : 16.1 kDa
Purity : >80%, as determined by SDS-PAGE and Coomassie blue staining
Stability : Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Storage : Store at -80 centigrade after receiving vials.
Concentration : >50 ug/mL as determined by microplate BCA method
Storage Buffer : 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Gene Name : Brms1 breast cancer metastasis-suppressor 1 [ Mus musculus (house mouse) ]
Official Symbol : Brms1
Synonyms : Brms1; breast cancer metastasis-suppressor 1; AV003220; AW554636; breast cancer metastasis-suppressor 1 homolog
Gene ID : 107392
mRNA Refseq : NM_134155
Protein Refseq : NP_598916
UniProt ID : Q99N20

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