Recombinant Mouse Brms1 Protein, MYC/DDK-tagged Brms1-328M

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Recombinant Mouse Brms1 Protein, MYC/DDK-tagged

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Cat.No. :	Brms1-328M
Product Overview :	Purified recombinant protein of full-length mouse breast cancer metastasis-suppressor 1 (cDNA clone MGC:6927 IMAGE:2811430), complete cds, with C-terminal MYC/DDK tag, expressed in HEK293T cells.
Description :	Transcriptional repressor. Down-regulates transcription activation by NF-kappa-B by promoting the deacetylation of RELA at 'Lys-310'. Promotes HDAC1 binding to promoter regions. Down-regulates expression of anti-apoptotic genes that are controlled by NF-kappa-B. Promotes apoptosis in cells that have inadequate adherence to a substrate, a process called anoikis, and may thereby inhibit metastasis.
Source :	HEK293T
Species :	Mouse
Tag :	MYC/DDK
Molecular Mass :	16.1 kDa
Purity :	>80%, as determined by SDS-PAGE and Coomassie blue staining
Stability :	Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Storage :	Store at -80 centigrade after receiving vials.
Concentration :	>50 ug/mL as determined by microplate BCA method
Storage Buffer :	25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Name :	Brms1 breast cancer metastasis-suppressor 1 [ Mus musculus (house mouse) ]
Official Symbol :	Brms1
Synonyms :	Brms1; breast cancer metastasis-suppressor 1; AV003220; AW554636; breast cancer metastasis-suppressor 1 homolog
Gene ID :	107392
mRNA Refseq :	NM_134155
Protein Refseq :	NP_598916
UniProt ID :	Q99N20