Recombinant Mouse Brms1 Protein, MYC/DDK-tagged


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Recombinant Mouse Brms1 Protein, MYC/DDK-tagged

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Cat.No. : Brms1-328M
Product Overview : Purified recombinant protein of full-length mouse breast cancer metastasis-suppressor 1 (cDNA clone MGC:6927 IMAGE:2811430), complete cds, with C-terminal MYC/DDK tag, expressed in HEK293T cells.
Description : Transcriptional repressor. Down-regulates transcription activation by NF-kappa-B by promoting the deacetylation of RELA at 'Lys-310'. Promotes HDAC1 binding to promoter regions. Down-regulates expression of anti-apoptotic genes that are controlled by NF-kappa-B. Promotes apoptosis in cells that have inadequate adherence to a substrate, a process called anoikis, and may thereby inhibit metastasis.
Source : HEK293T
Species : Mouse
Molecular Mass : 16.1 kDa
Purity : >80%, as determined by SDS-PAGE and Coomassie blue staining
Stability : Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Storage : Store at -80 centigrade after receiving vials.
Concentration : >50 ug/mL as determined by microplate BCA method
Storage Buffer : 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Gene Name : Brms1 breast cancer metastasis-suppressor 1 [ Mus musculus (house mouse) ]
Official Symbol : Brms1
Synonyms : Brms1; breast cancer metastasis-suppressor 1; AV003220; AW554636; breast cancer metastasis-suppressor 1 homolog
Gene ID : 107392
mRNA Refseq : NM_134155
Protein Refseq : NP_598916
UniProt ID : Q99N20
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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