Recombinant Mouse Car9 protein, His-tagged
Cat.No. : | Car9-7845M |
Product Overview : | Recombinant Mouse Car9 aa. (Glu88~Glu280 (Accession # Q8VHB5)) fused with N-terminal His tag was produced in E. coli cells. |
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Source : | E. coli |
Species : | Mouse |
Tag : | His |
Form : | Freeze-dried powder |
Molecular Mass : | 23 kDa as determined by SDS-PAGE reducing conditions. |
Protein length : | Glu88~Glu280 (Accession # Q8VHB5) |
Endotoxin : | <1.0EU per 1ug (determined by the LAL method) |
Purity : | >95% |
Characteristic : | The isoelectric point is 5.4. |
Applications : | SDS-PAGE; WB; ELISA; IP |
Stability : | The thermal stability is described by the loss rate of the target protein. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. (Referring from China Biological Products Standard, which was calculated by the Arrhenius equation.) The loss of this protein is less than 5% within the expiration date under appropriate storage condition. |
Storage : | Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months. |
Storage Buffer : | Supplied as liquid form in Phosphate buffered saline(PBS), pH 7.4. |
Reconstitution : | Reconstitute in sterile PBS, pH7.2-pH7.4. |
Gene Name : | Car9 carbonic anhydrase 9 [ Mus musculus (house mouse) ] |
Official Symbol : | Car9 |
Synonyms : | Car9; carbonic anhydrase 9; Ca9; CAIX; MN/CA9; CA-IX; carbonate dehydratase IX; carbonic anhydrase IX; membrane antigen MN homolog |
Gene ID : | 230099 |
mRNA Refseq : | NM_139305.2 |
Protein Refseq : | NP_647466.2 |
UniProt ID : | Q8VHB5 |
Products Types
◆ Recombinant Protein | ||
Car9-1962M | Recombinant Mouse Car9 Protein, Myc/DDK-tagged | +Inquiry |
CA9-1450C | Recombinant Cynomolgus CA9 protein, His-tagged | +Inquiry |
CA9-2272H | Recombinant Human CA9 Protein, MYC/DDK-tagged | +Inquiry |
CA9-117H | Recombinant Human CA9 Protein, His-tagged | +Inquiry |
CA9-116H | Recombinant Human CA9 Protein, His-tagged | +Inquiry |
◆ Lysates | ||
CA9-2189MCL | Recombinant Mouse CA9 cell lysate | +Inquiry |
CA9-1447CCL | Recombinant Canine CA9 cell lysate | +Inquiry |
CA9-3065HCL | Recombinant Human CA9 cell lysate | +Inquiry |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Write a reviewExceptional consistency, vital for our research's reliability.
Critical support for our protein analysis and quantification.
Unmatched accuracy in protein identification and sequencing.
Q&As (7)
Ask a questionThe HIF-1 signaling pathway primarily regulates CA9 in response to cellular oxygen levels.
CA9 aids in extracellular acidification, promoting tumor cell survival and invasion in acidic tumor microenvironments.
CA9 expression is upregulated by the hypoxia-inducible factor (HIF) under low oxygen conditions.
Elevated CA9 levels often correlate with poor prognosis in various cancers due to its role in tumor adaptation to hypoxia.
Potential modifications like glycosylation can be identified using techniques like mass spectrometry.
Several inhibitors, like acetazolamide derivatives, have been explored to target CA9 in cancer treatment.
CA9 helps tumors survive in hypoxic conditions by regulating pH through the conversion of CO2 to bicarbonate and protons.
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