Recombinant Mouse Casp9 Protein, MYC/DDK-tagged
Cat.No. : | Casp9-773M |
Product Overview : | Purified recombinant protein of full-length mouse caspase 9 (Casp9), with C-terminal MYC/DDK tag, expressed in HEK293T cells. |
- Specification
- Gene Information
- Related Products
Description : | This gene is part of a family of caspases, aspartate-specific cysteine proteases well studied for their involvement in immune and apoptosis signaling. This protein, the initiator caspase, is activated after cytochrome c release from mitochondria and targets downstream effectors. In mouse, deficiency of this gene can cause perinatal lethality. This protein may have a role in normal brain development. Alternative splicing results in multiple transcript variants that encode different protein isoforms. |
Source : | HEK293T |
Species : | Mouse |
Tag : | MYC/DDK |
Molecular Mass : | 50 kDa |
Purity : | >80% as determined by SDS-PAGE and Coomassie blue staining |
Stability : | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
Storage : | Store at -80 centigrade after receiving vials. |
Concentration : | >50 μg/mL as determined by microplate BCA method |
Storage Buffer : | 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol. |
Gene Name : | Casp9 caspase 9 [ Mus musculus (house mouse) ] |
Official Symbol : | Casp9 |
Synonyms : | Casp9; caspase 9; Mch6; APAF-3; CASP-9; AI115399; AW493809; ICE-LAP6; Caspase-9; caspase-9; ICE-like apoptotic protease 6; apoptotic protease Mch-6; apoptotic protease-activating factor 3; EC 3.4.22.62 |
Gene ID : | 12371 |
mRNA Refseq : | NM_015733 |
Protein Refseq : | NP_056548 |
UniProt ID : | Q8C3Q9 |
Products Types
◆ Recombinant Protein | ||
CASP9-2596H | Recombinant Human CASP9 Protein, His (Fc)-Avi-tagged | +Inquiry |
CASP9-1248M | Recombinant Mouse CASP9 Protein, His (Fc)-Avi-tagged | +Inquiry |
CASP9-0433H | Recombinant Human CASP9 Protein, GST-Tagged | +Inquiry |
CASP9-584H | Recombinant Human CASP9 | +Inquiry |
CASP9-0855H | Recombinant Human CASP9 Protein (Lys100-Thr270), N-SUMO tagged | +Inquiry |
◆ Lysates | ||
CASP9-7828HCL | Recombinant Human CASP9 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
- Q&As
- Reviews
Q&As (5)
Ask a questionDysregulation of CASP9 protein is associated with cancer, neurodegenerative diseases, and immune system disorders.
CASP9 protein is being investigated as a potential therapeutic target in autoimmune diseases to modulate immune cell apoptosis.
Dysregulation of CASP9 protein can lead to abnormal immune cell apoptosis, contributing to autoimmune diseases and immunodeficiency.
CASP9 protein is targeted using small molecule inhibitors and therapeutic antibodies to induce apoptosis in cancer cells.
Yes, genetic variations in the CASP9 gene can impact protein function and have been linked to disease susceptibility.
Customer Reviews (3)
Write a reviewIts purity and consistency have provided me with reliable and reproducible results, ensuring the accuracy of my research findings.
Their expertise and guidance have helped overcome hurdles, ensuring the smooth progress of my research.
The bands of proteins in Western Blotting experiments were very clear.
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