Recombinant Mouse Ccdc115 Protein, Myc/DDK-tagged

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Recombinant Mouse Ccdc115 Protein, Myc/DDK-tagged

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Cat.No. : Ccdc115-1986M
Product Overview : Purified recombinant protein of mouse full-length coiled-coil domain containing 115 (Ccdc115), with C-terminal MYC/DDK tag, expressed in HEK293T cells.
Description : Accessory component of the proton-transporting vacuolar (V)-ATPase protein pump involved in intracellular iron homeostasis. In aerobic conditions, required for intracellular iron homeostasis, thus triggering the activity of Fe2+ prolyl hydroxylase (PHD) enzymes, and leading to HIF1A hydroxylation and subsequent proteasomal degradation. Necessary for endolysosomal acidification and lysosomal degradation. May be involved in Golgi homeostasis.
Source : HEK293T
Species : Mouse
Tag : Myc/DDK
Molecular Mass : 19.7 kDa
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Stability : Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Storage : Store at -80 centigrade after receiving vials.
Concentration : >50 μg/mL as determined by microplate BCA method
Storage Buffer : 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Gene Name : Ccdc115 coiled-coil domain containing 115 [ Mus musculus (house mouse) ]
Official Symbol : Ccdc115
Synonyms : CCDC115; coiled-coil domain containing 115; coiled-coil domain-containing protein 115; coiled-coil protein 1; Ccp1; 2310061I09Rik
Gene ID : 69668
mRNA Refseq : NM_027159
Protein Refseq : NP_081435
UniProt ID : Q8VE99
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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