Recombinant Mouse Ccdc78 Protein, Myc/DDK-tagged

• Cat.No.: Ccdc78-2013M
• Product Overview: Purified recombinant protein of mouse full-length coiled-coil domain containing 78 (Ccdc78), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Species: Mouse
• Source: HEK293
• Tag: DDK&Myc
• Description: Component of the deuterosome, a structure that promotes de novo centriole amplification in multiciliated cells that can generate more than 100 centrioles. Deuterosome-mediated centriole amplification occurs in terminally differentiated multiciliated cells (G1/0) and not in S phase. Essential for centriole amplification and is required for CEP152 localization to the deuterosome.
• Molecular Mass: 49.9 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Ccdc78 coiled-coil domain containing 78 [ Mus musculus (house mouse) ]
• Official Symbol: Ccdc78
• Synonyms: Ccdc78; coiled-coil domain containing 78; Gm938; Gm950; coiled-coil domain-containing protein 78
• Gene ID: 381077
• mRNA Refseq: NM_001165929
• Protein Refseq: NP_001159401
• UniProt ID: D3Z5T1