Creative BioMart to Present at
                        BIO-Europe Spring Creative BioMart to Present at AACR Annual Meeting|Apr. 5-10, 2024|Booth #2953

Recombinant Mouse Cd274 Protein, mFc-tagged, low endotoxin, Alexa Fluor 488 conjugated

Cat.No. : Cd274-359MAF488
Product Overview : Alexa Fluor 488 conjugated recombinant Mouse Cd274 protein (Phe19-Thr238)(low endotoxin), fused to mouse IgG2a Fc tag at C-terminus, was expressed in human 293 cells (HEK293).
Unit
Price
Qty
  • Specification
  • Gene Information
  • Related Products
Description : Programmed cell death 1 ligand 1 (PDL1) is also known as B7-H, B7H1, MGC142294, MGC142296, PD-L1, PDCD1L1 and PDCD1LG1,which is a member of the growing B7 family of immune molecules and is involved in the regulation of cellular and humoral immune responses.PDL1 is a cell surface immunoglobulin superfamily with two Ig-like domains within the extracellular region and a short cytoplasmic domain. This protein is broadly expressed in the majority of peripheral tissues as well as hematopoietic cells. Interaction between PDL1 and its receptors belonging to the CD28 family of molecules provide both stimulatory and inhibitory signals in regulating T cell activation and tolerance. PDL1 may inhibit ongoing T-cell responses by inducing apoptosis and arresting cell-cycle progression.
Source : HEK293
Species : Mouse
Tag : mFc
Form : Lyophilized
Molecular Mass : The protein has a calculated MW of 51.8 kDa. The protein migrates as 65-85 kDa on a SDS-PAGE gel under reducing (R) condition due to glycosylation.
Protein length : 220
Endotoxin : < 0.1 EU/ μg by the LAL method.
Purity : > 95 % as determined by SDS-PAGE
Characteristic : Disulfide-linked homodimer
Labeled with Alexa Fluor 488 via amines
Excitation Wavelength: 488 nm
Emission Wavelength: 515­-545 nm
Storage : For long term storage, the product should be stored at lyophilized state at -20 centigrade or lower.
Please avoid repeated freeze-thaw cycles.
This product is stable after storage at:
-20 to -70 centigrade for 12 months in lyophilized state;
-70 centigrade for 3 months under sterile conditions after reconstitution.
Storage Buffer : Lyophilized from 0.22 μm filtered solution in PBS, pH7.4, 10% trehalose.
Reconstitution : It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 μg/μL. Centrifuge the vial at 4 centigrade before opening to recover the entire contents.
Gene Name : Cd274
Official Symbol : Cd274
Synonyms : B7h1; Pdl1; Pdcd1l1; Pdcd1lg1; A530045L16Rik
Gene ID : 60533
mRNA Refseq : NM_021893
Protein Refseq : NP_068693
UniProt ID : Q9EP73

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

Inquiry

  • Q&As
  • Reviews

Q&As (0)

Ask a question

Customer Reviews (0)

Write a review

Ask a Question for All Cd274 Products

Required fields are marked with *

My Review for All Cd274 Products

Required fields are marked with *

0

Inquiry Basket

cartIcon
logo

FOLLOW US

Terms and Conditions        Privacy Policy

Copyright © 2024 Creative BioMart. All Rights Reserved.

Contact Us

  • /

Stay Updated on the Latest Bioscience Trends