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Recombinant Mouse Cd46 protein, His & GST-tagged

Cat.No. : Cd46-6755M
Product Overview : Recombinant Mouse Cd46 aa. (Asp157~Arg365 (Accession # O88174)) fused with N-terminal His & GST tag was produced in E. coli cells.
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Source : E. coli
Species : Mouse
Tag : His&GST
Form : Freeze-dried powder
Molecular Mass : Predicted Molecular Mass: 55.2kDa.
Protein length : Asp157~Arg365
Endotoxin : <1.0EU per 1ug (determined by the LAL method)
Purity : >95%
Characteristic : The isoelectric point is 6.6.
Applications : SDS-PAGE; WB; ELISA; IP.
Stability : The thermal stability is described by the loss rate of the target protein. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. (Referring from China Biological Products Standard, which was calculated by the Arrhenius equation.) The loss of this protein is less than 5% within the expiration date under appropriate storage condition.
Storage : Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.
Storage buffer : Supplied as lyophilized form in PBS, pH7.4, containing 5% sucrose, 0.01% sarcosyl.
Reconstitution : Reconstitute in sterile PBS, pH7.2-pH7.4.
Gene Name : Cd46 CD46 antigen, complement regulatory protein [ Mus musculus (house mouse) ]
Official Symbol : Cd46
Synonyms : Mcp; membrane cofactor protein
Gene ID : 17221
mRNA Refseq : NM_010778.4
Protein Refseq : NP_034908.1
UniProt ID : O88174

Not For Human Consumption!

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Customer Reviews (3)

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Reviews
10/19/2022

    The CD46 protein offers numerous advantages in trials and research studies, making it an excellent choice for scientists in need of reliable and high-quality experimental materials.

    08/09/2019

      With the CD46 protein and its accompanying technical assistance, I am confident that I can achieve successful outcomes for my research endeavors.

      03/05/2019

        Its unique properties make CD46 an invaluable tool for investigating cellular signaling pathways, protein-protein interactions, and membrane dynamics.

        Q&As (5)

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        How does CD46 protein interact with other immune system components? 08/20/2021

        CD46 protein interacts with complement regulatory proteins and immune cells to regulate immune responses and maintain homeostasis.

        What are the potential side effects of targeting CD46 protein for therapy? 01/05/2020

        Potential side effects of targeting CD46 protein for therapy may include disturbances in immune regulation and increased susceptibility to infections.

        How does the CD46 protein contribute to immune regulation? 08/11/2018

        CD46 protein regulates the activation of complement system and modulates T cell responses, contributing to immune regulation.

        Can mutations in the CD46 gene lead to genetic disorders? 09/22/2017

        Mutations in the CD46 gene have been associated with genetic disorders such as atypical hemolytic uremic syndrome (aHUS) and other complement-related disorders.

        Is CD46 protein involved in cancer progression or treatment resistance? 08/07/2016

        CD46 protein has been implicated in cancer progression and treatment resistance, particularly in certain types of leukemia and solid tumors.

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