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Recombinant Mouse Cdh11 Protein, MYC/DDK-tagged

Cat.No. : Cdh11-859M
Product Overview : Purified recombinant protein of full-length mouse cadherin 11 (Cdh11), with C-terminal MYC/DDK tag, was expressed in HEK293T cells.
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Description : This gene encodes a type II classical cadherin and preproprotein that is proteolytically processed to generate a mature protein product. This protein product is an integral membrane protein that mediates calcium-dependent cell-cell adhesion, specifically in the context of bone development. Homozygous knockout mice for this gene exhibit impaired synovium development and reduced bone density. Multiple pseudogenes of this gene have been identified in the genome.
Source : HEK293T
Species : Mouse
Tag : MYC/DDK
Molecular Mass : 88.6 kDa
Purity : >80% as determined by SDS-PAGE and Coomassie blue staining
Stability : Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Storage : Store at -80 centigrade after receiving vials.
Concentration : >50 µg/mL as determined by microplate BCA method
Storage Buffer : 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Gene Name : Cdh11 cadherin 11 [ Mus musculus (house mouse) ]
Official Symbol : Cdh11
Synonyms : Cdh11; cadherin 11; Cad11; OSF-4; cadherin-11; OB-cadherin; osteoblast cadherin
Gene ID : 12552
mRNA Refseq : NM_009866
Protein Refseq : NP_033996
UniProt ID : P55288

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (5)

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Are there any specific diseases or conditions associated with abnormal CDH11 expression? 08/16/2021

Abnormal CDH11 expression is associated with conditions such as rheumatoid arthritis, osteoarthritis, and certain types of cancer.

Are there ongoing clinical trials targeting CDH11 for therapeutic purposes? 04/02/2021

Yes, there are clinical trials exploring the inhibition of CDH11 as a potential treatment strategy for diseases like rheumatoid arthritis and certain types of cancer.

How is CDH11 implicated in osteoarthritis? 08/29/2018

CDH11 is associated with osteoarthritis as it regulates the interaction between chondrocytes and synovial fibroblasts, contributing to the pathogenesis of the disease.

Where is CDH11 protein primarily expressed in the human body? 06/27/2017

CDH11 is predominantly found in mesenchymal tissues, such as the bone and synovium, and is involved in cell-cell adhesion in these tissues.

How can CDH11 be utilized as a biomarker in clinical diagnostics? 05/17/2016

CDH11 expression levels can be measured to assess the progression of certain diseases, such as osteoarthritis and certain cancers, providing valuable diagnostic information.

Customer Reviews (3)

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Reviews
03/22/2023

    The manufacturer's commitment to customer satisfaction is unmatched.

    02/26/2023

      Choosing the CDH11 protein from this manufacturer not only provides me with a superior product but also grants me access to unparalleled technical support.

      07/24/2017

        The manufacturer's commitment to customer satisfaction and their willingness to customize solutions based on specific experimental requirements is commendable.

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