Recombinant Mouse Celf3 Protein, Myc/DDK-tagged

• Cat.No.: Celf3-6574M
• Product Overview: Purified recombinant protein of mouse full-length trinucleotide repeat containing 4 (cDNA clone MGC:66604 IMAGE:6401356), complete cds, with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Species: Mouse
• Source: HEK293
• Tag: DDK&Myc
• Description: RNA-binding protein involved in the regulation of pre-mRNA alternative splicing. Mediates exon inclusion and/or exclusion in pre-mRNA that are subject to tissue-specific and developmentally regulated alternative splicing. Specifically activates exon 5 inclusion of cardiac isoforms of TNNT2 during heart remodeling at the juvenile to adult transition. Activates the splicing of MAPT/Tau exon 10. Binds to muscle-specific splicing enhancer (MSE) intronic sites flanking the alternative exon 5 of TNNT2 pre-mRNA.
• Molecular Mass: 53.5 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Celf3 CUGBP, Elav-like family member 3 [ Mus musculus (house mouse) ]
• Official Symbol: Celf3
• Synonyms: Celf3; CUGBP, Elav-like family member 3; BRU; ERD; Tnr; CAGH; CAGH4; ERDA4; ETR-1; Tnrc4; BRUNOL1; 4930415M08Rik; CUGBP Elav-like family member 3; CUG-BP- and ETR-3-like factor 3; ELAV-type RNA-binding protein 1; RNA-binding protein BRUNOL-1; VCUGBP, Elav-like family member 3; bruno-like protein 1; trinucleotide repeat containing 4; trinucleotide repeat-containing gene 4 protein
• Gene ID: 78784
• mRNA Refseq: NM_172434
• Protein Refseq: NP_766022
• UniProt ID: Q8CIN6