Recombinant Mouse Cers3 Protein, Myc/DDK-tagged

• Cat.No.: Cers3-2122M
• Product Overview: Purified recombinant protein of mouse full-length ceramide synthase 3 (Cers3), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Description: Ceramide synthase that catalyzes formation of ceramide from sphinganine and acyl-CoA substrates, with high selectivity toward very-long (C22:0-C24:0) and ultra long chain (more than C26:0) as acyl donor. It is crucial for the synthesis of ultra long-chain ceramides in the epidermis, to maintain epidermal lipid homeostasis and terminal differentiation.
• Source: HEK293T
• Species: Mouse
• Tag: Myc/DDK
• Molecular Mass: 50.5 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Cers3 ceramide synthase 3 [ Mus musculus (house mouse) ]
• Official Symbol: Cers3
• Synonyms: Cers3; ceramide synthase 3; L; T3; Cer; T3L; Gm488; Lass3; mCerS3; 4930550L11Rik; ceramide synthase 3; LAG1 homolog, ceramide synthase 3; LAG1 longevity assurance homolog 3; dihydroceramide synthase 3; longevity assurance homolog 3; related to TRH3; sphingosine N-acyltransferase CERS3; EC 2.3.1.24
• Gene ID: 545975
• mRNA Refseq: NM_001164201
• Protein Refseq: NP_001157673
• UniProt ID: Q1A3B0