Recombinant Mouse Chordc1 Protein, Myc/DDK-tagged

• Cat.No.: Chordc1-2154M
• Product Overview: Purified recombinant protein of mouse full-length cysteine and histidine-rich domain (CHORD)-containing, zinc-binding protein 1 (Chordc1), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Description: Regulates centrosome duplication, probably by inhibiting the kinase activity of ROCK2. Proposed to act as co-chaperone for HSP90. May play a role in the regulation of NOD1 via a HSP90 chaperone complex. In vitro, has intrinsic chaperone activity. This function may be achieved by inhibiting association of ROCK2 with NPM1. Plays a role in ensuring the localization of the tyrosine kinase receptor EGFR to the plasma membrane, and thus ensures the subsequent regulation of EGFR activity and EGF-induced actin cytoskeleton remodeling. Involved in stress response. Prevents tumorigenesis.
• Source: HEK293T
• Species: Mouse
• Tag: Myc/DDK
• Molecular Mass: 37.4 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Chordc1 cysteine and histidine-rich domain (CHORD)-containing, zinc-binding protein 1 [ Mus musculus (house mouse) ]
• Official Symbol: Chordc1
• Synonyms: CHORDC1; cysteine and histidine-rich domain (CHORD)-containing, zinc-binding protein 1; cysteine and histidine-rich domain-containing protein 1; protein morgana; CHORD-containing protein 1; CHORD domain-containing protein 1; Chp-1; morgana; AA409036; 1110001O09Rik
• Gene ID: 66917
• mRNA Refseq: NM_025844
• Protein Refseq: NP_080120
• UniProt ID: Q9D1P4