Recombinant Mouse Clstn1 Protein, Myc/DDK-tagged
Cat.No. : | Clstn1-2198M |
Product Overview : | Purified recombinant protein of mouse full-length calsyntenin 1 (Clstn1), with C-terminal MYC/DDK tag, expressed in HEK293T cells. |
- Specification
- Gene Information
- Related Products
Description : | Induces KLC1 association with vesicles and functions as a cargo in axonal anterograde transport. Complex formation with APBA2 and APP, stabilizes APP metabolism and enhances APBA2-mediated suppression of beta-APP40 secretion, due to the retardation of intracellular APP maturation. In complex with APBA2 and C99, a C-terminal APP fragment, abolishes C99 interaction with PSEN1 and thus APP C99 cleavage by gamma-secretase, most probably through stabilization of the direct interaction between APBA2 and APP. As intracellular fragment AlcICD, suppresses APBB1-dependent transactivation stimulated by APP C-terminal intracellular fragment (AICD), most probably by competing with AICD for APBB1-binding. May modulate calcium-mediated postsynaptic signals. |
Source : | HEK293T |
Species : | Mouse |
Tag : | Myc/DDK |
Molecular Mass : | 109.3 kDa |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Stability : | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
Storage : | Store at -80 centigrade after receiving vials. |
Concentration : | >50 μg/mL as determined by microplate BCA method |
Storage Buffer : | 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol. |
Gene Name : | Clstn1 calsyntenin 1 [ Mus musculus (house mouse) ] |
Official Symbol : | Clstn1 |
Synonyms : | CLSTN1; calsyntenin 1; calsyntenin-1; alc-alpha; alcadein alpha; alcadein-alpha; Cst-1; Cstn1; 1810034E21Rik |
Gene ID : | 65945 |
mRNA Refseq : | NM_023051 |
Protein Refseq : | NP_075538 |
UniProt ID : | Q9EPL2 |
Products Types
◆ Recombinant Protein | ||
CLSTN1-1124R | Recombinant Rat CLSTN1 Protein, His (Fc)-Avi-tagged | +Inquiry |
CLSTN1-2691H | Recombinant Human CLSTN1 Protein, His (Fc)-Avi-tagged | +Inquiry |
CLSTN1-3262H | Recombinant Human CLSTN1 Protein, MYC/DDK-tagged | +Inquiry |
CLSTN1-1771M | Recombinant Mouse CLSTN1 Protein, His (Fc)-Avi-tagged | +Inquiry |
CLSTN1-1518H | Recombinant Human CLSTN1 Protein, GST-tagged | +Inquiry |
◆ Lysates | ||
CLSTN1-369HCL | Recombinant Human CLSTN1 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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