"Col2a1" Related Products


Recombinant Mouse Col2a1 protein, His-tagged

Cat.No.: Col2a1-36M
Product Overview: Recombinant Mouse Col2a1 fused with His tag was expressed in HEK293.
Description: This gene encodes the alpha-1 subunit of the fibril-forming type II collagen, the major component of cartilage and the vitreous humor of the eye. The encoded preproprotein forms homotrimeric, triple helical procollagen that undergoes proteolytic processing during fibirl formation. Mice harboring certain mutations in this gene exhibit severe chondrodysplasia characterized by short limbs and trunch, craniofacial deformities and cleft palate. A complete lack of the encoded protein in mice results in postnatal lethality. Alternative splicing results in multiple transcript variants encoding different isoforms that may undergo similar proteolytic processing.
Source: HEK293
Species: Mouse
Tag: His
Form: Tris-based buffer, 50% glycerol
Purity: >90% (SDS-PAGE)
Storage: Store at -20 centigrade, for extended storage, conserve at -20 centigrade or -80 centigrade. Repeated freezing and thawing is not recommended. Store working aliquots at 4 centigrade for up to one week.
Gene Name: Col2a1 collagen, type II, alpha 1 [ Mus musculus ]
Official Symbol: Col2a1
Synonyms: COL2A1; collagen, type II, alpha 1; collagen alpha-1(II) chain; chondrocalcin; alpha-1 type II collagen; disproportionate micromelia; procollagen, type II, alpha 1; Dmm; Col2; Del1; Col2a; Col2a-1; M100856; Rgsc856; MGC90638;
Gene ID: 12824
mRNA Refseq: NM_001113515
Protein Refseq: NP_001106987
UniProt ID: P28481
Chromosome Location: 15 F1; 15 53.97 cM
Pathway: Amoebiasis, organism-specific biosystem; Amoebiasis, conserved biosystem; Axon guidance, organism-specific biosystem; Developmental Biology, organism-specific biosystem; ECM-receptor interaction, organism-specific biosystem; ECM-receptor interaction, conserved biosystem; Endochondral Ossification, organism-specific biosystem;
Function: extracellular matrix structural constituent; platelet-derived growth factor binding;

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Optional requirements on this protein    +Expand
C-fusion    N-fusion   Non-tagged
His    GST   Fc   Others
<1.0 eu/μg    <0.1 eu/μg   <0.01 eu/μg   Not required
Monomer Isolation    Dimer Isolation    Not required
>80% by SDS-PAGE    >90% by SDS-PAGE   >95% by SDS-PAGE   Others

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