Recombinant Mouse Cpe Protein, MYC/DDK-tagged Cpe-931M

Recombinant Mouse Cpe Protein, MYC/DDK-tagged

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Recombinant Mouse Cpe Protein, MYC/DDK-tagged

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Cat.No. : Cpe-931M
Product Overview : Purified recombinant protein of full-length mouse carboxypeptidase E (Cpe), with C-terminal MYC/DDK tag, was expressed in HEK293T cells.
Description : This gene encodes carboxypeptidase E, a prohormone-processing exopeptidase found in secretory granules of endocrine and neuroendocrine cells. The encoded preproprotein undergoes proteolytic processing to generate a mature, functional enzyme that cleaves the C-terminal basic residues of protein substrates. A missense mutation in this gene is responsible for the obesity phenotype in a mouse model known as the "fat mouse." Mice lacking the functional product of this gene exhibit impaired processing of multiple peptide hormones such as proinsulin, prodynorphin, proneurotensin, promelanin-concentrating hormone and pro-opiomelanocortin.
Source : HEK293T
Species : Mouse
Tag : MYC/DDK
Molecular Mass : 53.7 kDa
Purity : >80% as determined by SDS-PAGE and Coomassie blue staining
Stability : Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Storage : Store at -80 centigrade after receiving vials.
Concentration : >50 µg/mL as determined by microplate BCA method
Storage Buffer : 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Gene Name : Cpe carboxypeptidase E [ Mus musculus (house mouse) ]
Official Symbol : Cpe
Synonyms : Cpe; carboxypeptidase E; CPH; fat; Cph1; Cph-1; R74677; NF-alpha1; carboxypeptidase E; carboxypeptidase H; enkephalin convertase; prohormone-processing carboxypeptidase; EC 3.4.17.10
Gene ID : 12876
mRNA Refseq : NM_013494
Protein Refseq : NP_038522
UniProt ID : Q00493

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