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Recombinant Mouse CR1L Protein (41-405 aa), His-tagged

Cat.No. : CR1L-2324M
Product Overview : Recombinant Mouse CR1L Protein (41-405 aa) is produced by E. coli expression system. This protein is fused with a 6xHis tag at the N-terminal. Protein Description: Partial.
  • Specification
  • Gene Information
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Description : Acts as a cofactor for complement factor I, a serine protease which protects autologous cells against complement-mediated injury by cleaving C3b and C4b deposited on host tissue. Also acts as a decay-accelerating factor, preventing the formation of C4b2a and C3bBb, the amplification convertases of the complement cascade. Plays a crucial role in early embryonic development by maintaining fetomaternal tolerance. Also acts as a costimulatory factor for T-cells which favors IL-4 secretion.
Source : E. coli
Species : Mouse
Tag : His
Form : Tris-based buffer,50% glycerol
Molecular Mass : 44.5 kDa
Protein length : 41-405 aa
AA Sequence : ELRGGLGKHGHTVHREPAVNRLCAD SKRWSGLPVSAQRPFPMGHCPAPSQ LPSAKPINLTDESMFPIGTYLLYEC LPGYIKRQFSITCKQDSTWTSAEDK CIRKQCKTPSDPENGLVHVHTGIQF GSRINYTCNQGYRLIGSSSAVCVIT DQSVDWDTEAPICEWIPCEIPPGIP NGDFFSSTREDFHYGMVVTYRCNTD ARGKALFNLVGEPSLYCTSNDGEIG VWSGPPPQCIELNKCTPPPYVENAV MLSENRSLFSLRDIVEFRCHPGFIM KGASSVHCQSLNKWEPELPSCFKGV ICRLPQEMSGFQKGLGMKKEYYYGE NVTLECEDGYTLEGSSQSQCQSDGS WNPLLAKCVSRSISG
Purity : > 85% as determined by SDS-PAGE.
Notes : Repeated freezing and thawing is not recommended. Store working aliquots at 4 centigrade for up to one week.
Storage : The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20 centigrade/-80 centigrade. The shelf life of lyophilized form is 12 months at -20 centigrade/-80 centigrade.
Concentration : A hardcopy of COA will be sent along with the products. Please refer to it for detailed information.
Gene Name : Cr1l complement component (3b/4b) receptor 1-like [ Mus musculus (house mouse) ]
Official Symbol : CR1L
Synonyms : Cr1l; Mcp; Crry; mCRY;
Gene ID : 12946
mRNA Refseq : NM_013499
Protein Refseq : NP_038527
UniProt ID : Q64735

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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