| Cat.No. : |
CR1L-2324M |
| Product Overview : |
Recombinant Mouse CR1L Protein (41-405 aa) is produced by E. coli expression system. This protein is fused with a 6xHis tag at the N-terminal. Protein Description: Partial. |
| Description : |
Acts as a cofactor for complement factor I, a serine protease which protects autologous cells against complement-mediated injury by cleaving C3b and C4b deposited on host tissue. Also acts as a decay-accelerating factor, preventing the formation of C4b2a and C3bBb, the amplification convertases of the complement cascade. Plays a crucial role in early embryonic development by maintaining fetomaternal tolerance. Also acts as a costimulatory factor for T-cells which favors IL-4 secretion. |
| Source : |
E. coli |
| Species : |
Mouse |
| Tag : |
His |
| Form : |
Tris-based buffer,50% glycerol |
| Molecular Mass : |
44.5 kDa |
| Protein length : |
41-405 aa |
| AA Sequence : |
ELRGGLGKHG HTVHREPAVN RLCADSKRWS GLPVSAQRPF PMGHCPAPSQ LPSAKPINLT DESMFPIGTY LLYECLPGYI KRQFSITCKQ DSTWTSAEDK CIRKQCKTPS DPENGLVHVH TGIQFGSRIN YTCNQGYRLI GSSSAVCVIT DQSVDWDTEA PICEWIPCEI PPGIPNGDFF SSTREDFHYG MVVTYRCNTD ARGKALFNLV GEPSLYCTSN DGEIGVWSGP PPQCIELNKC TPPPYVENAV MLSENRSLFS LRDIVEFRCH PGFIMKGASS VHCQSLNKWE PELPSCFKGV ICRLPQEMSG FQKGLGMKKE YYYGENVTLE CEDGYTLEGS SQSQCQSDGS WNPLLAKCVS RSISG |
| Purity : |
> 85% as determined by SDS-PAGE. |
| Notes : |
Repeated freezing and thawing is not recommended. Store working aliquots at 4 centigrade for up to one week. |
| Storage : |
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20 centigrade/-80 centigrade. The shelf life of lyophilized form is 12 months at -20 centigrade/-80 centigrade. |
| Concentration : |
A hardcopy of COA will be sent along with the products. Please refer to it for detailed information. |
| Figure : |
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
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