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Recombinant Mouse Cr2 protein, His & T7-tagged

Cat.No. : Cr2-837M
Product Overview : Recombinant Mouse Cr2 aa. (Cys463~Asp665 (Accession # P19070)) fused with N-terminal His & T7 tag was produced in E. coli cells.
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Source : E. coli
Species : Mouse
Tag : His & T7
Form : Freeze-dried powder
Molecular Mass : Predicted Molecular Mass: 26.4kDa
Protein length : Cys463~Asp665 (Accession # P19070)
Endotoxin : <1.0EU per 1µg (determined by the LAL method)
Purity : >95%
Characteristic : The isoelectric point is 6.7.
Applications : SDS-PAGE; WB; ELISA; IP.
Stability : The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
Storage : Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.
Storage buffer : Supplied as lyophilized form in 20mM Tris, 150mM NaCl, pH8.0, containing 1mM EDTA, 1mM DTT, 0.01% sarcosyl, 5% trehalose, and preservative.
Reconstitution : Reconstitute in sterile ddH2O.
Gene Name : Cr2 complement receptor 2 [ Mus musculus (house mouse) ]
Official Symbol : Cr2
Synonyms : Cr1; C3DR; CD21; CD35; Cr-1; Cr-2; complement C3d receptor; complement receptor type 1; expressed in B lymphocytes; complement receptor type 2
Gene ID : 12902
mRNA Refseq : NM_007758.2
Protein Refseq : NP_031784.1
UniProt ID : P19070

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (7)

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What is the potential of targeting CR2 in therapeutic interventions for immune-related disorders? 12/15/2022

Therapeutically targeting CR2 could adjust immune responses in autoimmune conditions and transplantations.

How does CR2 interact with complement pathways and what are the implications for immune response? 07/20/2021

CR2's interaction with complement pathways influences both innate and adaptive immunity, affecting phagocytosis and inflammation.

How do genetic variations in the CR2 gene affect its protein function and disease susceptibility? 12/26/2019

Genetic variations in CR2 can alter its function, affecting susceptibility to infections and autoimmunity.

What impact does CR2 have on B-cell activation and maturation? 08/02/2019

CR2 is integral in B-cell activation and maturation, influencing adaptive immunity.

How does CR2 expression influence autoimmune diseases? 04/02/2019

Changes in CR2 expression can affect immune self-tolerance, contributing to autoimmune diseases.

What factors regulate the expression of CR2 on immune cells? 08/02/2018

Cytokines and immune cell activation states regulate CR2 expression, impacting immune responses.

What is the role of CR2 protein in immune system function? 11/05/2017

CR2 facilitates B-cell activation and antigen presentation by binding to complement component C3d, enhancing antibody responses.

Customer Reviews (3)

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Reviews
02/11/2022

    Essential partner in our protein research.

    03/01/2020

      Saves time and resources in our experiments.

      11/02/2019

        Trustworthy results, crucial for decision-making.

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