Recombinant Mouse Cr2 protein, His & T7-tagged
Cat.No. : | Cr2-837M |
Product Overview : | Recombinant Mouse Cr2 aa. (Cys463~Asp665 (Accession # P19070)) fused with N-terminal His & T7 tag was produced in E. coli cells. |
- Specification
- Gene Information
- Related Products
Source : | E. coli |
Species : | Mouse |
Tag : | His & T7 |
Form : | Freeze-dried powder |
Molecular Mass : | Predicted Molecular Mass: 26.4kDa |
Protein length : | Cys463~Asp665 (Accession # P19070) |
Endotoxin : | <1.0EU per 1µg (determined by the LAL method) |
Purity : | >95% |
Characteristic : | The isoelectric point is 6.7. |
Applications : | SDS-PAGE; WB; ELISA; IP. |
Stability : | The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition. |
Storage : | Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months. |
Storage buffer : | Supplied as lyophilized form in 20mM Tris, 150mM NaCl, pH8.0, containing 1mM EDTA, 1mM DTT, 0.01% sarcosyl, 5% trehalose, and preservative. |
Reconstitution : | Reconstitute in sterile ddH2O. |
Gene Name : | Cr2 complement receptor 2 [ Mus musculus (house mouse) ] |
Official Symbol : | Cr2 |
Synonyms : | Cr1; C3DR; CD21; CD35; Cr-1; Cr-2; complement C3d receptor; complement receptor type 1; expressed in B lymphocytes; complement receptor type 2 |
Gene ID : | 12902 |
mRNA Refseq : | NM_007758.2 |
Protein Refseq : | NP_031784.1 |
UniProt ID : | P19070 |
Products Types
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Cr2-938M | Recombinant Mouse Cr2 Protein, MYC/DDK-tagged | +Inquiry |
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CR2-836H | Recombinant Human CR2 protein, His & GST-tagged | +Inquiry |
◆ Lysates | ||
CR2-2201HCL | Recombinant Human CR2 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (7)
Ask a questionTherapeutically targeting CR2 could adjust immune responses in autoimmune conditions and transplantations.
CR2's interaction with complement pathways influences both innate and adaptive immunity, affecting phagocytosis and inflammation.
Genetic variations in CR2 can alter its function, affecting susceptibility to infections and autoimmunity.
CR2 is integral in B-cell activation and maturation, influencing adaptive immunity.
Changes in CR2 expression can affect immune self-tolerance, contributing to autoimmune diseases.
Cytokines and immune cell activation states regulate CR2 expression, impacting immune responses.
CR2 facilitates B-cell activation and antigen presentation by binding to complement component C3d, enhancing antibody responses.
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