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Recombinant Mouse CXCR4 Protein, His-GST-tagged

Cat.No. : CXCR4-40M
Product Overview : Recombinant Mouse CXCR4 Protein(NP_001343438.1)(Asp269~Ser359), fused to two N-terminal tags, His tag and GST tag, was expressed in E. coli.
  • Specification
  • Gene Information
  • Related Products
Source : E. coli
Species : Mouse
Tag : His-GST
Form : PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
Molecular Mass : 40kDa as determined by SDS-PAGE reducing conditions.
Protein length : Asp269~Ser359
Endotoxin : <1.0EU per 1µg (determined by the LAL method)
Purity : > 90%
Applications : Positive Control; Immunogen; SDS-PAGE; WB.
If bio-activity of the protein is needed, please check active protein.
Notes : The kit is designed for research use only, we will not be responsible for any issue if the kit was used in clinical diagnostic or any other procedures.
Stability : The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
Storage : Avoid repeated freeze/thaw cycles.
Store at 2-8°C for one month.
Aliquot and store at -80°C for 12 months.
Concentration : 200µg/mL
Reconstitution : It is recommended that sterile water be added to the vial to prepare a stock solution of 0.25 mg/ml. Centrifuge the vial at 4°C before opening to recover the entire contents.
Gene Name : Cxcr4 chemokine (C-X-C motif) receptor 4 [ Mus musculus (house mouse) ]
Official Symbol : CXCR4
Synonyms : fu; Sdf; Cmka; PB-C; CD184; LESTR; Sdf1r; CXC-R4; CXCR-4; Cmkar4; PB-CKR; b2b220C; b2b220Clo; PBSF/SDF-1
Gene ID : 12767
mRNA Refseq : NM_001356509.1
Protein Refseq : NP_001343438.1
UniProt ID : P70658

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (7)

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How does CXCR4 participate in chemotaxis and migration of immune cells, particularly in the context of the immune response? 01/26/2022

CXCR4 participates in chemotaxis and migration of immune cells, facilitating their movement toward specific tissues during the immune response.

Are there specific chemokines or ligands that CXCR4 binds to, influencing its role in immune cell activation and recruitment? 01/09/2020

Specific chemokines or ligands, such as CXCL12, bind to CXCR4, influencing its role in immune cell activation and recruitment.

In which cellular compartments is CXCR4 predominantly localized, especially within immune cells? 06/14/2019

CXCR4 is predominantly localized on the cell surface of immune cells, particularly within the membrane of T cells and monocytes.

What diseases or conditions are associated with dysregulation or abnormal expression of CXCR4, especially in the immune system? 03/27/2019

Dysregulation or abnormal expression of CXCR4 is associated with diseases such as cancer, HIV/AIDS, and autoimmune disorders, particularly affecting immune cell function.

Are there therapeutic implications or potential targets related to CXCR4 in diseases involving immune dysregulation and inflammation? 06/28/2018

There are potential therapeutic implications related to CXCR4 in diseases involving immune dysregulation and inflammation, making it a target for drug development.

How does CXCR4 contribute to the regulation of inflammatory responses and immune cell trafficking in various tissues? 08/30/2017

CXCR4 contributes to the regulation of inflammatory responses and immune cell trafficking in various tissues, influencing the outcome of immune reactions.

What is the primary function of C-X-C chemokine receptor type 4 (CXCR4) in cellular processes and immune responses? 06/27/2016

C-X-C chemokine receptor type 4 (CXCR4) plays a crucial role in cellular processes, primarily contributing to immune responses and cell migration.

Customer Reviews (3)

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Reviews
04/07/2022

    The responsive customer support team provided quick resolutions to any queries or issues we encountered.

    10/28/2021

      The product's cost-effectiveness and clear instructions were instrumental in our experimental design.

      10/29/2018

        We found the product's straightforward protocols highly conducive to seamless integration into our lab work.

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