Recombinant Mouse CXCR4 Protein, His-GST-tagged
Cat.No. : | CXCR4-40M |
Product Overview : | Recombinant Mouse CXCR4 Protein(NP_001343438.1)(Asp269~Ser359), fused to two N-terminal tags, His tag and GST tag, was expressed in E. coli. |
- Specification
- Gene Information
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Source : | E. coli |
Species : | Mouse |
Tag : | His-GST |
Form : | PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300. |
Molecular Mass : | 40kDa as determined by SDS-PAGE reducing conditions. |
Protein length : | Asp269~Ser359 |
Endotoxin : | <1.0EU per 1µg (determined by the LAL method) |
Purity : | > 90% |
Applications : | Positive Control; Immunogen; SDS-PAGE; WB. If bio-activity of the protein is needed, please check active protein. |
Notes : | The kit is designed for research use only, we will not be responsible for any issue if the kit was used in clinical diagnostic or any other procedures. |
Stability : | The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition. |
Storage : | Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months. |
Concentration : | 200µg/mL |
Reconstitution : | It is recommended that sterile water be added to the vial to prepare a stock solution of 0.25 mg/ml. Centrifuge the vial at 4°C before opening to recover the entire contents. |
Gene Name : | Cxcr4 chemokine (C-X-C motif) receptor 4 [ Mus musculus (house mouse) ] |
Official Symbol : | CXCR4 |
Synonyms : | fu; Sdf; Cmka; PB-C; CD184; LESTR; Sdf1r; CXC-R4; CXCR-4; Cmkar4; PB-CKR; b2b220C; b2b220Clo; PBSF/SDF-1 |
Gene ID : | 12767 |
mRNA Refseq : | NM_001356509.1 |
Protein Refseq : | NP_001343438.1 |
UniProt ID : | P70658 |
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Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (7)
Ask a questionCXCR4 participates in chemotaxis and migration of immune cells, facilitating their movement toward specific tissues during the immune response.
Specific chemokines or ligands, such as CXCL12, bind to CXCR4, influencing its role in immune cell activation and recruitment.
CXCR4 is predominantly localized on the cell surface of immune cells, particularly within the membrane of T cells and monocytes.
Dysregulation or abnormal expression of CXCR4 is associated with diseases such as cancer, HIV/AIDS, and autoimmune disorders, particularly affecting immune cell function.
There are potential therapeutic implications related to CXCR4 in diseases involving immune dysregulation and inflammation, making it a target for drug development.
CXCR4 contributes to the regulation of inflammatory responses and immune cell trafficking in various tissues, influencing the outcome of immune reactions.
C-X-C chemokine receptor type 4 (CXCR4) plays a crucial role in cellular processes, primarily contributing to immune responses and cell migration.
Customer Reviews (3)
Write a reviewThe responsive customer support team provided quick resolutions to any queries or issues we encountered.
The product's cost-effectiveness and clear instructions were instrumental in our experimental design.
We found the product's straightforward protocols highly conducive to seamless integration into our lab work.
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