Recombinant Mouse Dnajb6 Protein, Myc/DDK-tagged

• Cat.No.: Dnajb6-2600M
• Product Overview: Purified recombinant protein of mouse full-length DnaJ heat shock protein family (Hsp40) member B6 (Dnajb6), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Description: Plays an indispensable role in the organization of KRT8/KRT18 filaments. Acts as an endogenous molecular chaperone for neuronal proteins including huntingtin. Suppresses aggregation and toxicity of polyglutamine-containing, aggregation-prone proteins. Has a stimulatory effect on the ATPase activity of HSP70 in a dose-dependent and time-dependent manner and hence acts as a co-chaperone of HSP70. Also reduces cellular toxicity and caspase-3 activity.
• Source: HEK293T
• Species: Mouse
• Tag: Myc/DDK
• Molecular Mass: 27 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Dnajb6 DnaJ heat shock protein family (Hsp40) member B6 [ Mus musculus (house mouse) ]
• Official Symbol: Dnajb6
• Synonyms: DNAJB6; DnaJ (Hsp40) homolog, subfamily B, member 6; dnaJ homolog subfamily B member 6; HSJ-2; heat shock protein J2; mammalian relative of DnaJ; Mrj; mDj4; MGC102124
• Gene ID: 23950
• mRNA Refseq: NM_001127367
• Protein Refseq: NP_001120839
• UniProt ID: O54946