Recombinant Mouse Dnmt3l Protein, Myc/DDK-tagged

• Cat.No.: Dnmt3l-2623M
• Product Overview: Purified recombinant protein of mouse full-length DNA (cytosine-5-)-methyltransferase 3-like (Dnmt3l), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Description: CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. This gene encodes a nuclear protein that is a catalytically inactive regulatory factor of DNA methyltransferases. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
• Source: HEK293T
• Species: Mouse
• Tag: Myc/DDK
• Molecular Mass: 48 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Dnmt3l DNA (cytosine-5-)-methyltransferase 3-like [ Mus musculus (house mouse) ]
• Official Symbol: Dnmt3l
• Synonyms: DNMT3L; DNA (cytosine-5-)-methyltransferase 3-like; DNA (cytosine-5)-methyltransferase 3-like; ecat7; D6Ertd14e; MGC102308
• Gene ID: 54427
• mRNA Refseq: NM_019448
• Protein Refseq: NP_062321
• UniProt ID: Q9CWR8