Recombinant Mouse Dph1 Protein, MYC/DDK-tagged
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Cat.No. : | Dph1-586M |
Product Overview : | Purified recombinant protein of full-length mouse diphthamide biosynthesis 1 (Dph1), with C-terminal MYC/DDK tag, expressed in HEK293T cells. |
Description : | Required for the first step in the synthesis of diphthamide, a post-translational modification of histidine which occurs in translation elongation factor 2. When overexpressed, suppresses colony formation ability and growth rate of ovarian cancer cells. Acts also as a tumor suppressor in lung and breast cancers. Plays a role in embryonic growth, organogenesis and postnatal survival. |
Source : | HEK293T |
Species : | Mouse |
Tag : | MYC/DDK |
Molecular Mass : | 48.5 kDa |
Purity : | >80% as determined by SDS-PAGE and Coomassie blue staining |
Stability : | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
Storage : | Store at -80 centigrade after receiving vials. |
Concentration : | >50 μg/mL as determined by microplate BCA method |
Storage Buffer : | 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol. |
Gene Name : | Dph1 diphthamide biosynthesis 1 [ Mus musculus (house mouse) ] |
Official Symbol : | Dph1 |
Synonyms : | Dph1; diphthamide biosynthesis 1; Ovca1; Dph2l1; AW551873; 2310011M22Rik; 4930488F09Rik; 2-(3-amino-3-carboxypropyl)histidine synthase subunit 1; DPH1 homolog; DPH2-like 1; S-adenosyl-L-methionine:L-histidine 3-amino-3-carboxypropyltransferase 1; diphthamide biosynthesis protein 1; diphthamide biosynthesis protein 2 homolog-like 1; diphtheria toxin resistance protein 1; diptheria toxin resistance protein required for diphthamide biosynthesis (Saccharomyces)-like 1; mmDph1; ovarian cancer-associated gene 1 protein homolog; EC 2.5.1.108 |
Gene ID : | 116905 |
mRNA Refseq : | NM_144491 |
Protein Refseq : | NP_652762 |
UniProt ID : | Q5NCQ5 |
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