Recombinant Mouse Drc1 Protein, Myc/DDK-tagged

• Cat.No.: Drc1-2658M
• Product Overview: Purified recombinant protein of mouse full-length dynein regulatory complex subunit 1 (Drc1), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Species: Mouse
• Source: HEK293
• Tag: DDK&Myc
• Description: Component of the nexin-dynein regulatory complex (N-DRC) a key regulator of ciliary/flagellar motility which maintains the alignment and integrity of the distal axoneme and regulates microtubule sliding in motile axonemes. Plays a critical role in the assembly of N-DRC and also stabilizes the assembly of multiple inner dynein arms and radial spokes. Coassembles with CCDC65/DRC2 to form a central scaffold needed for assembly of the N-DRC and its attachment to the outer doublet microtubules.
• Molecular Mass: 88.5 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Drc1 dynein regulatory complex subunit 1 [ Mus musculus (house mouse) ]
• Official Symbol: Drc1
• Synonyms: Drc1; dynein regulatory complex subunit 1; Gm1060; Ccdc164; b2b1654C; b2b1654Clo; dynein regulatory complex protein 1; coiled-coil domain containing 164; coiled-coil domain-containing protein 164
• Gene ID: 381738
• mRNA Refseq: NM_001033460
• Protein Refseq: NP_001028632
• UniProt ID: Q3USS3