Recombinant Mouse Dusp13 Protein, Myc/DDK-tagged

• Cat.No.: Dusp13-2682M
• Product Overview: Purified recombinant protein of mouse full-length dual specificity phosphatase 13 (Dusp13), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Description: Members of the protein-tyrosine phosphatase superfamily cooperate with protein kinases to regulate cell proliferation and differentiation. This superfamily is separated into two families based on the substrate that is dephosphorylated. One family, the dual specificity phosphatases (DSPs) acts on both phosphotyrosine and phosphoserine/threonine residues. This gene encodes different but related DSP proteins through the use of non-overlapping open reading frames, alternate splicing, and presumed different transcription promoters. Expression of the distinct proteins from this gene has been found to be tissue specific and the proteins may be involved in postnatal development of specific tissues. A protein encoded by the upstream ORF was found in skeletal muscle, whereas the encoded protein from the downstream ORF was found only in testis. In humans, a similar pattern of expression was found. Multiple alternatively spliced transcript variants were described, but the full-length sequence of only some were determined.
• Source: HEK293T
• Species: Mouse
• Tag: Myc/DDK
• Molecular Mass: 29.7 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Dusp13 dual specificity phosphatase 13 [ Mus musculus (house mouse) ]
• Official Symbol: Dusp13
• Synonyms: DUSP13; dual specificity phosphatase 13; dual specificity protein phosphatase 13; Dsp13-like protein; muscle-restricted DSP; testis- and skeletal muscle-specific DSP; dual specificity tyrosine phosphatase TS-DSP6; dual-specificity tyrosine phosphatase TS-DSP6; dual specificity protein phosphatase isoform MDSP; testis and skeletal muscle-specific dual specificity phosphatase; MDSP; TMDP; Gm1203; TS-DSP6; LMW-DSP6
• Gene ID: 27389
• mRNA Refseq: NM_013849
• Protein Refseq: NP_038877
• UniProt ID: Q9QYJ7